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Bioengineering Program Scholarly Works: Recent submissions
Now showing items 101-120 of 154
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Photoacoustic detection of functional responses in the motor cortex of awake behaving monkey during forelimb movement
(Society of Photo-optical Instrumentation Engineers, 2012-10-22)Photoacoustic (PA) imaging was applied to detect the neuronal activity in the motor cortex of an awake, behaving monkey during forelimb movement. An adult macaque monkey was trained to perform a reach-to-grasp task while ... -
Peptide-directed co-assembly of nanoprobes on multimaterial patterned solid surfaces
(Royal Society of Chemistry, 2012-02-16)Biocombinatorially selected solid-binding peptides, through their unique material affinity and selectivity, are a promising platform for building up complex hierarchical assemblies of nanoscale materials and molecular ... -
Cementomimetics—constructing a cementum-like biomineralized microlayer via amelogenin-derived peptides
(Nature Publishing Group, 2012-06-29)Cementum is the outer-, mineralized-tissue covering the tooth root and an essential part of the system of periodontal tissue that anchors the tooth to the bone. Periodontal disease results from the destructive behavior of ... -
Direct interaction of ligand–receptor pairs specifying stomatal patterning
(Cold Spring Harbor Laboratory Press, 2012-01-12)Valves on the plant epidermis called stomata develop according to positional cues, which likely involve putative ligands (EPIDERMAL PATTERNING FACTORS [EPFs]) and putative receptors (ERECTA family receptor kinases and TOO ... -
Diet-induced metabolic hamster model of nonalcoholic fatty liver disease
(Dove Medical Press, 2011-06-03)Obesity, hypercholesterolemia, elevated triglycerides, and type 2 diabetes are major risk factors for metabolic syndrome. Hamsters, unlike rats or mice, respond well to diet-induced obesity, increase body mass and adiposity ... -
Computational Knee Ligament Modeling Using Experimentally Determined Zero-Load Lengths
(Bentham Open, 2012-04-02)This study presents a subject-specific method of determining the zero-load lengths of the cruciate and collateral ligaments in computational knee modeling. Three cadaver knees were tested in a dynamic knee simulator. The ... -
Engineered Escherichia coli Silver-Binding Periplasmic Protein That Promotes Silver Tolerance
(American Society for Microbiology, 2012-01-27)Silver toxicity is a problem that microorganisms face in medical and environmental settings. Through exposure to silver compounds, some bacteria have adapted to growth in high concentrations of silver ions. Such adapted ... -
Laser enhanced high-intensity focused ultrasound thrombolysis: An in vitro study
(Acoustical Society of America, 2013-01-17)Laser-enhanced thrombolysis by high intensity focused ultrasound (HIFU) treatment was studied in vitro with bovine blood clots. To achieve laser-enhanced thrombolysis, laser light was employed to illuminate the sample ... -
Photoacoustic contrast imaging of biological tissues with nanodiamonds fabricated for high near-infrared absorbance
(Society of Photo-optical Instrumentation Engineers, 2013-02-12)Radiation-damaged nanodiamonds (DNDs) are potentially ideal optical contrast agents for photoacoustic (PA) imaging in biological tissues due to their low toxicity and high optical absorbance. PA imaging contrast agents ... -
Effect of the degenerative state of the intervertebral disk on the impact characteristics of human spine segments
(Frontiers, 2013-12-16)Models of the dynamic response of the lumbar spine have been used to examine vertebral fractures (VFx) during falls and whole body vibration transmission in the occupational setting. Although understanding the viscoelastic ... -
Human umbilical cord mesenchymal stromal cells in regenerative medicine
(BioMed Central, 2013-11-25)Cells of the human umbilical cord offer tremendous potential for improving human health. Cells from the Wharton’s jelly (umbilical cord stroma) in particular, referred to as human umbilical cord mesenchymal stromal cells ... -
Poly(vinylamine) microgels: pH-responsive particles with high primary amine contents
(Royal Society of Chemistry, 2013-01-16)pH-responsive microgels are crosslinked polymer colloid particles that swell when the pH approaches the pKa of the polybase or polyacid chains. Poly(vinylamine) (PVAM) has the highest primary amine content of all ... -
Fabrication of nanofibres using bioinspired microfluidic spinning
(Royal Society of Chemistry, 2013-09-06) -
Posterior composite restoration update: focus on factors influencing form and function
(Dove Medical Press, 2013-05-15)Restoring posterior teeth with resin-based composite materials continues to gain popularity among clinicians, and the demand for such aesthetic restorations is increasing. Indeed, the most common aesthetic alternative to ... -
Laser-enhanced cavitation during high intensity focused ultrasound: An in vivo study
(American Institute of Physics, 2013-04-01)Laser-enhanced cavitation during high intensity focused ultrasound (HIFU) was studied in vivo using a small animal model. Laser light was employed to illuminate the sample concurrently with HIFU radiation. The resulting ... -
Enhanced cavitation by using two consecutive ultrasound waves at different frequencies
(American Institute of Physics, 2014-11-10)Efficient and noninvasive generation of cavitation bubbles in soft tissue is a challenging task due to the lack of cavitation nuclei (i.e., pre-existing gas bubbles). In this study, we present a method to generate and ... -
Dynamic Measurements of Membrane Insertion Potential of Synthetic Cell Penetrating Peptide/pDNA/Ca2+ Complexes
(Elsevier, 2015-01-27)Noncovalent complexation of plasmid DNA (pDNA) using cell penetrating peptides (CPPs) has been less explored due to the relatively large complex size formed and the low-level gene expression. Here, condensing synthetic CPP ... -
Cost effective filamentous phage based immunization nanoparticles displaying a full-length hepatitis B virus surface antigen
(Scientific Research Publishing, 2014)Hepatitis B virus (HBV) is one of the major causes of chronic hepatitis, cirrhosis and liver cancer. In combating HBV infections, HBV diagnosis and vaccination are therefore critical. The hepatitis B virus surface antigen ... -
Suppression of Tumorigenesis: Modulation of Inflammatory Cytokines by Oral Administration of Microencapsulated Probiotic Yogurt Formulation
(Hindawi Publishing Corporation, 2010-08)The objective of this study was to examine the ability of a novel microencapsulated probiotic yogurt formulation to suppress the intestinal inflammation. We assessed its anticancer activity by screening interleukin-1, 6, ... -
Intramyocardial sustained delivery of placental growth factor using nanoparticles as a vehicle for delivery in the rat infarct model
(Dove Medical Press, 2011-10-31)Acute myocardial ischemia results in scar formation with ventricular dilatation and eventually heart failure. Placental growth factor (PlGF) is reported to stimulate angiogenesis and improve cardiac function. In this study, ...