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    Peptide-directed co-assembly of nanoprobes on multimaterial patterned solid surfaces

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    Hnilova_multimaterial_patterned2012.pdf (3.668Mb)
    Issue Date
    2012-02-16
    Author
    Hnilova, Marketa
    So, Christopher R.
    Oren, Ersin Emre
    Wilson, Brandon R.
    Kacar, Turgay
    Tamerler, Candan
    Sarikaya, Mehmet
    Publisher
    Royal Society of Chemistry
    Type
    Article
    Article Version
    Scholarly/refereed, publisher version
    Metadata
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    Abstract
    Biocombinatorially selected solid-binding peptides, through their unique material affinity and selectivity, are a promising platform for building up complex hierarchical assemblies of nanoscale materials and molecular probes, targeted to specific practical solid surfaces. Here, we demonstrate the material-specific characteristics of engineered gold-binding and silica-binding peptides through co-assembly onto micro- and nano-patterned gold surfaces on silica substrates. To build hierarchical nanostructures on patterned solid surfaces, we utilize peptides as molecular tools and monitor their behavior by either conjugating biotin to them for specific affinity to streptavidin-coated QDot nanoparticles or labelling them with small fluorescent labels. This biomimetic peptide-based approach could be used as an alternative to conventional chemical coupling and surface functionalization techniques with substantial advantages, allowing simultaneous assembly of two or more inorganic nano-entities and/or molecular probes onto patterned inorganic solid substrates. The results have significant implications in a wide range of potential applications, including controlled assembly of hybrid nanostructures in bionanophotonic and biosensing devices.
    Description
    This is the published version. Copyright 2012 Royal Society of Chemistry
    URI
    http://hdl.handle.net/1808/18874
    DOI
    https://doi.org/10.1039/C2SM06426J
    Collections
    • Bioengineering Program Scholarly Works [144]
    • Mechanical Engineering Scholarly Works [135]
    Citation
    Hnilova, Marketa, Christopher R. So, E. Emre Oren, Brandon R. Wilson, Turgay Kacar, Candan Tamerler, and Mehmet Sarikaya. "Peptide-directed Co-assembly of Nanoprobes on Multimaterial Patterned Solid Surfaces." Soft Matter 8.16 (2012): 4327. http://dx.doi.org/10.1039/C2SM06426J

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    KU Libraries
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    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
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    Contact KU ScholarWorks
    785-864-8983
    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    Image Credits
     

     

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