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Bioengineering Program Scholarly Works: Recent submissions
Now showing items 81-100 of 154
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A model for the dynamics of gas bubbles in soft tissue
(Acoustical Society of America, 2005)Understanding the behavior of cavitation bubbles driven by ultrasonic fields is an important problem in biomedical acoustics. Keller-Miksis equation, which can account for the large amplitude oscillations of bubbles, is ... -
Nonlinear dynamics of gas bubbles in viscoelastic media
(Acoustical Society of America, 2005-04-11)Understanding the behavior of cavitation bubbles driven by ultrasonic fields is an important problem in biomedical acoustics. The Keller–Miksis equation for nonlinear bubble dynamics is combined with the Voigt model for ... -
Photoacoustic tomography of a rat cerebral cortex with a ring-based ultrasonic virtual point detector
(Society of Photo-optical Instrumentation Engineers, 2007-12-18)We image a rat cerebral cortex in situ by using a ring-based ultrasonic virtual point detector developed previously. Compared to the image generated by a finite-aperture detector, the image generated by the virtual point ... -
Ring-based ultrasonic virtual point detector with applications to photoacoustic tomography
(American Institute of Physics, 2007)An ultrasonic virtual point detector is constructed using the center of a ring transducer. The virtual point detector provides ideal omnidirectional detection free of any aperture effect. Compared with a real point detector, ... -
Photoacoustic tomography of small animal brain with a curved array transducer
(Society of Photo-optical Instrumentation Engineers, 2009-09-16)We present the application of a curved array photoacoustic tomographic imaging system that can provide rapid, high-resolution photoacoustic imaging of small animal brains. The system is optimized to produce a B-mode, 90-deg ... -
Growth of melanoma brain tumors monitored by photoacoustic microscopy
(Society of Photo-optical Instrumentation Engineers, 2010-08-13)Melanoma is a primary malignancy that is known to metastasize to the brain and often causes death. The ability to image the growth of brain melanoma in vivo can provide new insights into its evolution and response to ... -
In vivo photoacoustic imaging of chemotherapy-induced apoptosis in squamous cell carcinoma using a near-infrared caspase-9 probe
(Society of Photo-optical Instrumentation Engineers (SPIE), 2011-10-27)Anti-cancer drugs typically exert their pharmacological effect on tumors by inducing apoptosis, or programmed cell death, within the cancer cells. However, no tools exist in the clinic for detecting apoptosis in real time. ... -
Functional photoacoustic imaging to observe regional brain activation induced by cocaine hydrochloride
(Society of Photo-optical Instrumentation Engineers (SPIE), 2011-09-13)Photoacoustic microscopy (PAM) was used to detect small animal brain activation in response to drug abuse. Cocaine hydrochloride in saline solution was injected into the blood stream of Sprague Dawley rats through tail ... -
Threshold voltage control in organic thin film transistors with dielectric layer modified by a genetically engineered polypeptide
(American Institute of Physics, 2010)Precise control over the threshold voltage of pentacene-based organic thin film transistors was achieved by inserting a genetically engineered quartz-binding polypeptide at the semiconductor-dielectric interface. A 30 V ... -
In vitro comparison of conventional film and direct digital imaging in the detection of approximal caries
(British Institute of Radiology, 2007)Objectives: To compare the diagnostic accuracy of conventional film, unenhanced direct digital and inversion grayscale direct digital imaging in the detection of approximal caries. Methods: 150 approximal surfaces of ... -
High-resolution magnetic resonance imaging and diffusion tensor imaging of the porcine temporomandibular joint disc
(British Institute of Radiology, 2014-01-28)Objectives: Diffusion tensor imaging (DTI) is an MRI modality for characterizing the property, microstructural organization and function in tissues such as the brain and spinal cord. Prior to this investigation, DTI had ... -
Towards comprehensive structural motif mining for better fold annotation in the "twilight zone" of sequence dissimilarity
(BioMed Central, 2009-01-30)Background Automatic identification of structure fingerprints from a group of diverse protein structures is challenging, especially for proteins whose divergent amino acid sequences may fall into the "twilight-" or ... -
Constructing non-stationary Dynamic Bayesian Networks with a flexible lag choosing mechanism
(BioMed Central, 2010-10-07)Background Dynamic Bayesian Networks (DBNs) are widely used in regulatory network structure inference with gene expression data. Current methods assumed that the underlying stochastic processes that generate the gene ... -
Application of kernel functions for accurate similarity search in large chemical databases
(BioMed Central, 2010)Background Similaritysearch in chemical structure databases is an important problem with many applications in chemical genomics, drug design, and efficient chemical probe screening among others. It is widely believed ... -
Immunohistochemical characterization of the rabbit tracheal cartilages
(Scientific Research Publishing, 2010-10)The objective of this study was to immunohistochemically elucidate the major extracellular matrix constituents of rabbit tracheal cartilage. The impetus for this project is the need for crucial design and validation criteria ... -
Chondrogenic differentiation of stem cells in human umbilical cord stroma with PGA and PLLA scaffolds
(Scientific Research Publishing, 2012-11)The stem cells in the umbilical cord stroma, or Wharton’s jelly, are referred to as human umbilical cord mesenchymal stromal cells (hUCMSCs) and have been shown to differentiate along a chondrogenic lineage. The aim of ... -
A Review of Gene Delivery and Stem Cell Based Therapies for Regenerating Inner Ear Hair Cells
(MDPI, 2011)Sensory neural hearing loss and vestibular dysfunction have become the most common forms of sensory defects, affecting millions of people worldwide. Developing effective therapies to restore hearing loss is challenging, ... -
Grade 1 spondylolisthesis and interspinous device placement: removal in six patients and analysis of current data
(Medknow Publications, 2015-04-02)In the treatment of patients with Grade 1 spondylolisthesis, the use of interspinous devices has been controversial for nearly a decade. Several authors have suggested that Grade 1 spondylolisthesis be considered a ... -
Ice-sheet bed 3-D tomography
(International Glaciological Society, 2010-04)Information on bed topography and basal conditions is essential to developing the next-generation ice-sheet models needed to generate a more accurate estimate of ice-sheet contribution to sea-level rise. Synthetic aperture ... -
Enhanced-heating effect during photoacoustic imaging-guided high-intensity focused ultrasound
(American Institute of Physics, 2011)Photoacoustic imaging(PAI) technique has been used to monitor thermal lesion formation during high-intensity focused ultrasound (HIFU) treatment. While previous studies focused on photoacousticdetection of changes in ...