Enhanced-heating effect during photoacoustic imaging-guided high-intensity focused ultrasound

Abstract

Photoacoustic imaging(PAI) technique has been used to monitor thermal lesion formation during high-intensity focused ultrasound (HIFU) treatment. While previous studies focused on photoacousticdetection of changes in temperature during HIFU treatment, we report an enhanced-heating effect when PAI is used to monitor HIFU treatment. We found that the temperature induced by HIFU could be significantly enhanced when the diagnostic laser system for photoacousticdetection was operating during HIFU treatment. This finding demonstrates an advantage of using PAI to guide HIFU therapy.