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Molecular Biosciences: Recent submissions
Now showing items 441-460 of 887
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Effect of urea on Bacillus coli, Bacillus typhosus, and Staphylococcus aureus
(University of Kansas, 1922) -
Protein metabolism of hemolytic streptococci
(University of Kansas, 1921) -
Studies upon epidemic paralysis among guinea pigs
(University of Kansas, 1921) -
Studies on Bacillus pyocyaneus
(University of Kansas, 1922) -
Reduce, Reuse, Recycle: The tale of two Wnts and the lone C. elegans Syndecan, SDN-1
(University of Kansas, 2015-05-31)Heparan sulfate proteoglycans (HSPGs) are cell adhesion molecules that have been shown to be involved in a myriad of different aspects of development such as embryogenesis, dorsal-ventral axon guidance and cell migration. ... -
NMR-Based Computational Studies of Membrane Proteins in Explicit Membranes
(University of Kansas, 2015-05-31)Since nuclear magnetic resonance (NMR) spectroscopy data, including solution NMR from micelles and solid-state NMR from bilayers, provide valuable structural and dynamics information of membrane proteins, they are commonly ... -
Association of low-activity MAOA allelic variants with violent crime in incarcerated offenders
(Elsevier, 2014-11)The main enzyme for serotonin degradation, monoamine oxidase (MAO) A, has recently emerged as a key biological factor in the predisposition to impulsive aggression. Male carriers of low-activity variants of the main ... -
When the Love Hormone Leads to Violence: Oxytocin Increases Intimate Partner Violence Inclinations Among High Trait Aggressive People
(SAGE Publications, 2014-02-12)Does oxytocin influence intimate partner violence (IPV)? Clues from prior research suggest that oxytocin increases prosocial behavior, but this effect is reversed among people with aggressive tendencies or in situations ... -
Specific Control of Endogenous cCF10 Pheromone by a Conserved Domain of the pCF10-Encoded Regulatory Protein PrgY in Enterococcus faecalis
(American Society for Microbiology, 2005-07)Conjugative transfer of Enterococcus faecalis plasmid pCF10 is induced by the heptapeptide pheromone cCF10. cCF10 produced by plasmid-free recipient cells is detected by pCF10-containing donor cells, which respond by ... -
Analysis of the Amino Acid Sequence Specificity Determinants of the Enterococcal cCF10 Sex Pheromone in Interactions with the Pheromone-Sensing Machinery
(American Society for Microbiology, 2007-02)The level of expression of conjugation genes in Enterococcus faecalis strains carrying the pheromone-responsive transferable plasmid pCF10 is determined by the ratio in the culture medium of two types of signaling peptides, ... -
Characterization of the Sequence Specificity Determinants Required for Processing and Control of Sex Pheromone by the Intramembrane Protease Eep and the Plasmid-Encoded Protein PrgY
(American Society for Microbiology, 2008-02-01)Conjugative transfer of the Enterococcus faecalis plasmid pCF10 is induced by the peptide pheromone cCF10 when recipient-produced cCF10 is detected by donors. cCF10 is produced by proteolytic processing of the signal ... -
Quorum-Sensing Control of Antibiotic Synthesis in Burkholderia thailandensis
(American Society for Microbiology, 2009-04-17)The genome of Burkholderia thailandensis codes for several LuxR-LuxI quorum-sensing systems. We used B. thailandensis quorum-sensing deletion mutants and recombinant Escherichia coli to determine the nature of the signals ... -
Mutational Analysis of Burkholderia thailandensis Quorum Sensing and Self-Aggregation
(American Society for Microbiology, 2009-07-31)Acyl-homoserine lactone (acyl-HSL) quorum-sensing signaling is common to many Proteobacteria. Acyl-HSLs are synthesized by the LuxI family of synthases, and the signal response is mediated by members of the LuxR family of ... -
Bactobolin Resistance Is Conferred by Mutations in the L2 Ribosomal Protein
(American Society for Microbiology, 2012-12-18)Burkholderia thailandensis produces a family of polyketide-peptide molecules called bactobolins, some of which are potent antibiotics. We found that growth of B. thailandensis at 30°C versus that at 37°C resulted in increased ... -
Cystic fibrosis–adapted Pseudomonas aeruginosa quorum sensing lasR mutants cause hyperinflammatory responses
(American Association for the Advancement of Science, 2015-07-31)Cystic fibrosis lung disease is characterized by chronic airway infections with the opportunistic pathogen Pseudomonas aeruginosa and severe neutrophilic pulmonary inflammation. P. aeruginosa undergoes extensive genetic ... -
Quorum Sensing Protects Pseudomonas aeruginosa against Cheating by Other Species in a Laboratory Coculture Model
(American Society for Microbiology, 2015-10)Many species of bacteria use a cell-cell communication system called quorum sensing (QS) to coordinate group activities. QS systems frequently regulate the production of exoproducts. Some of these products, such as proteases, ... -
A Burkholderia thailandensis Acyl-Homoserine Lactone-Independent Orphan LuxR Homolog That Activates Production of the Cytotoxin Malleilactone
(American Society for Microbiology, 2015-11)Burkholderia thailandensis has three acyl-homoserine lactone (AHL) LuxR-LuxI quorum-sensing circuits and two orphan LuxR homologs. Orphans are LuxR-type transcription factors that do not have cognate LuxI-type AHL synthases. ... -
Multi-task and Multi-view Learning for Predicting Adverse Drug Reactions
(University of Kansas, 2012-12-31)Adverse drug reactions (ADRs) present a major concern for drug safety and are a major obstacle in modern drug development. They account for about one-third of all late-stage drug failures, and approximately 4% of all new ... -
Studies in immunity I. Thermo-stabile and so-called thermolabile hemolysins
(University of Kansas, 1917)