Molecular Biosciences Dissertations and Theses: Recent submissions
Now showing items 121-140 of 270
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NMR-Based Computational Studies of Membrane Proteins in Explicit Membranes
(University of Kansas, 2015-05-31)Since nuclear magnetic resonance (NMR) spectroscopy data, including solution NMR from micelles and solid-state NMR from bilayers, provide valuable structural and dynamics information of membrane proteins, they are commonly ... -
Multi-task and Multi-view Learning for Predicting Adverse Drug Reactions
(University of Kansas, 2012-12-31)Adverse drug reactions (ADRs) present a major concern for drug safety and are a major obstacle in modern drug development. They account for about one-third of all late-stage drug failures, and approximately 4% of all new ... -
Studies in immunity I. Thermo-stabile and so-called thermolabile hemolysins
(University of Kansas, 1917) -
The classification of white and slightly pigmented staphylococci according to sugars
(University of Kansas, 1920) -
Studies on the paratyphoid-enteritidis group
(University of Kansas, 1920) -
Mechanism of cap-snatching in hantaviruses
(University of Kansas, 2014-12-31)Hantaviruses are enveloped RNA viruses belong to the Family Bunyaviridae, which cause hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS) in humans. The hantavirus genome consists ... -
MODULATING PROTEIN FUNCTION WITH SMALL MOLECULES THROUGH COMPUTATIONAL AND EXPERIMENTAL DESIGN TECHNIQUES
(University of Kansas, 2014-12-31)The ability to modulate protein function using exogenous small molecules is a longstanding goal in chemical biology. Selective activation or inhibition of a particular protein function can help elucidate crucial molecular ... -
The bacterial flora of enamel slip
(University of Kansas, 1922) -
Role of Enterococcal Membrane Proteins in Cell-Cell Communication and Stress Adaptation
(University of Kansas, 2014-12-31)Enterococcus faecalis has recently emerged as one of the leading causes of nosocomial infections. The ability to tolerate a variety of antibiotics and environmental stresses (biotic and abiotic) combined with a plethora ... -
Studies on Bacillus typhosus : a comparison of their cultural and serological relations
(University of Kansas, 1920.) -
Studies in organisms of colon-aerogenes group : Isolated from various sources /
(University of Kansas, 1919.) -
Elucidation of the Mechanisms of Nucleosome Binding and Repositioning by a Chromatin Remodeler: Monomeric ISWI Remodels Nucleosomes Through a Random Walk
(University of Kansas, 2014-05-31)The regulation of chromatin structure is controlled by a family of molecular motors called chromatin remodelers. The ability of these enzymes to remodel chromatin structure is dependent on their ability to couple ATP binding ... -
Developing A Bitwise Macromolecular Assembly Simulator
(University of Kansas, 2014-08-31)Macromolecular machines play fundamental roles in many cellular tasks, from intracellular transport to protein synthesis and degradation. The majority of these machines must adopt a particular quaternary structure in order ... -
IDENTIFYING AND CHARACTERIZING THE ROLES OF TRANSMEMBRANE PROTEINS IN DIRECTING ASYMMETRIC Q NEUROBLAST MIGRATIONS
(University of Kansas, 2014-08-31)Migration of neurons is essential for proper nervous system development. Defects in neural development can lead to several neurological disorders. Hence it is important to understand the mechanism of neuronal migration ... -
MECHANISM AND FUNCTION OF SPLICEOSOMAL CLEAVAGE IN FISSION YEAST
(University of Kansas, 2013-08-31)Telomerase is the ribonucleoprotein complex that replenishes lost DNA sequences at the ends of chromosomes. At its core, telomerase consists of an RNA subunit (TERC) that provides the template and a catalytic protein ... -
Nova Mediates Experience Dependent Processing of Orb2A mRNA
(University of Kansas, 2013-08-31)Memory serves the vital function of associating disparate stimuli to modify future behavior for fitness. For instance, Drosophila melanogaster can learn to associate neutral odors with sweet metabolically available sugars ... -
CHARACTERIZATION OF THE STRUCTURE, FUNCTION, AND PROTEIN-PROTEIN INTERACTIONS INVOLVED IN THE ASSEMBLY OF THE TYPE III SECRETION SYSTEM TIP COMPLEX AND THE TRANSLOCON OF SALMONELLA AND SHIGELLA
(University of Kansas, 2013-08-31)The type III secretion system (T3SS) is a macromolecular structure assembled by many Gram-negative bacteria in order to invade target host cells. A functional T3SS contains a syringe-like structural component known as the ... -
Driving Functional Behavioral Recovery Using Activity-Dependent Stimulation
(University of Kansas, 2012-12-31)The purpose of this project was to determine if artificially linking spared motor and sensory areas following a cortical lesion would lead to increased behavioral recovery on a skilled reaching task. Sensory-motor integration ... -
Hormonal regulation of microRNA expression in the ovary
(University of Kansas, 2012-12-31)The ovary is a dynamic organ that is charged with the responsibility of producing a viable gamete so that the circle of life can be reproduced for future generations. The ovary is also responsible for producing, secreting, ...