ATTENTION: The software behind KU ScholarWorks is being upgraded to a new version. Starting July 15th, users will not be able to log in to the system, add items, nor make any changes until the new version is in place at the end of July. Searching for articles and opening files will continue to work while the system is being updated.
If you have any questions, please contact Marianne Reed at mreed@ku.edu .
Molecular Biosciences: Recent submissions
Now showing items 401-420 of 887
-
Epidemic parotitis
(University of Kansas, 1925) -
A study of the bacterial flora of green vegetables
(University of Kansas, 1923) -
EGL-20/Wnt and MAB-5/Hox Act Sequentially to Inhibit Anterior Migration of Neuroblasts in C. elegans
(Public Library of Science, 2016-02-10)Directed neuroblast and neuronal migration is important in the proper development of nervous systems. In C. elegans the bilateral Q neuroblasts QR (on the right) and QL (on the left) undergo an identical pattern of cell ... -
Structure of a Bacterial Virus DNA-Injection Protein Complex Reveals a Decameric Assembly with a Constricted Molecular Channel
(Public Library of Science, 2016-02-16)The multi-layered cell envelope structure of Gram-negative bacteria represents significant physical and chemical barriers for short-tailed phages to inject phage DNA into the host cytoplasm. Here we show that a DNA-injection ... -
A study of the agglutinins in human sera for hemolytic streptococci from scarlet fever
(University of Kansas, 1925) -
Antigenic value of lung extract
(University of Kansas, 1924) -
Structures of minute virus of mice replication initiator protein N-terminal domain: insights into DNA nicking and origin binding
(Elsevier, 2016-02-01)Members of the Parvoviridae family all encode a non-structural protein 1 (NS1) that directs replication of single-stranded viral DNA, packages viral DNA into capsid, and serves as a potent transcriptional activator. Here ... -
piRNAs Are Associated with Diverse Transgenerational Effects on Gene and Transposon Expression in a Hybrid Dysgenic Syndrome of D. virilis
(Public Library of Science, 2015-08)Sexual reproduction allows transposable elements (TEs) to proliferate, leading to rapid divergence between populations and species. A significant outcome of divergence in the TE landscape is evident in hybrid dysgenic ... -
Simulated unbound structures for benchmarking of protein docking in the dockground resource
(BioMed Central, 2015-07-31)Background Proteins play an important role in biological processes in living organisms. Many protein functions are based on interaction with other proteins. The structural information is important for adequate description ... -
piRNAs Are Associated with Diverse Transgenerational Effects on Gene and Transposon Expression in a Hybrid Dysgenic Syndrome of D. virilis
(Public Library of Science, 2015-08-04)Sexual reproduction allows transposable elements (TEs) to proliferate, leading to rapid divergence between populations and species. A significant outcome of divergence in the TE landscape is evident in hybrid dysgenic ... -
Replication of an Autonomous Human Parvovirus in Non-dividing Human Airway Epithelium Is Facilitated through the DNA Damage and Repair Pathways
(Public Library of Science, 2016-01-14)Human bocavirus 1 (HBoV1) belongs to the genus Bocaparvovirus of the Parvoviridae family, and is an emerging human pathogenic respiratory virus. In vitro, HBoV1 infects well-differentiated/polarized primary human airway ... -
DARC 2.0: Improved Docking and Virtual Screening at Protein Interaction Sites
(Public Library of Science, 2015-07-16)Over the past decade, protein-protein interactions have emerged as attractive but challenging targets for therapeutic intervention using small molecules. Due to the relatively flat surfaces that typify protein interaction ... -
DARC 2.0: Improved Docking and Virtual Screening at Protein Interaction Sites
(Public Library of Science, 2015-07-16)Over the past decade, protein-protein interactions have emerged as attractive but challenging targets for therapeutic intervention using small molecules. Due to the relatively flat surfaces that typify protein interaction ... -
Text Mining for Protein Docking
(Public Library of Science, 2015-12-09)The rapidly growing amount of publicly available information from biomedical research is readily accessible on the Internet, providing a powerful resource for predictive biomolecular modeling. The accumulated data on ... -
A quantitative assay to monitor HSV-1 ICP0 ubiquitin ligase activity in vitro
(Elsevier, 2015-11-15)The ubiquitin–proteasome system is an essential cellular process that plays a fundamental role in the regulation of protein stability. This pathway is tightly controlled by a sequential cascade of enzymatic steps that ... -
The Imidazoquinoline Toll-Like Receptor-7/8 Agonist Hybrid-2 Potently Induces Cytokine Production by Human Newborn and Adult Leukocytes
(Public Library of Science, 2015-08-14)Background: Newborns and young infants are at higher risk for infections than adults, and manifest suboptimal vaccine responses, motivating a search for novel immunomodulators and/or vaccine adjuvants effective in ... -
Glycosylation Effects on FSH-FSHR Interaction Dynamics: A Case Study of Different FSH Glycoforms by Molecular Dynamics Simulations
(Public Library of Science, 2015-09-24) -
Enhancements to the Rosetta Energy Function Enable Improved Identification of Small Molecules that Inhibit Protein-Protein Interactions
(Public Library of Science, 2015-10-20)Protein-protein interactions are among today’s most exciting and promising targets for therapeutic intervention. To date, identifying small-molecules that selectively disrupt these interactions has proven particularly ... -
Role of Prolactin and Prolactin Receptor Signaling in Colorectal Tumorigenesis
(University of Kansas, 2014-08-31)Hormones are critical regulatory factors produced by the body to regulate diverse physiological activities such as energy homeostasis, growth and differentiation of a diverse array of tissues, sexual maturation and development ... -
Genetic Susceptibility to the Murine Model of Retinopathy of Prematurity: Identification of a Novel Role of Tyrosinase in Retinal Angiogenic Regulation
(University of Kansas, 2013-08-31)Retinopathy of Prematurity (ROP) is a major cause of vision loss in the pediatric population. A growing body of evidence suggests that a heritable component contributes to risk of disease development. Identification of ...