Life Span Institute: Recent submissions
Now showing items 81-100 of 248
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Recruitment issues in a randomized controlled exercise trial targeting wheelchair users
(Elsevier, 2011-03)This paper describes recruitment challenges and lessons learned in conducting a randomized controlled exercise trial in the absence of direct access to a clinical population. One hundred thirty-five wheelchair users were ... -
Cardiorespiratory fitness and preserved medial temporal lobe volume in Alzheimer's Disease
(Lippincott, Williams & Wilkins, 2009)Exercise and cardiorespiratory (CR) fitness may moderate age-related regional brain changes in nondemented older adults (ND). The relationship of fitness to Alzheimer's disease (AD) related brain change is understudied, ... -
Rhesus macaque model of chronic opiate dependence and neuro-AIDS: longitudinal assessment of auditory brainstem responses and visual evoked potentials
(Springer Verlag, 2009-06)Our work characterizes the effects of opiate (morphine) dependence on auditory brainstem and visual evoked responses in a rhesus macaque model of neuro-AIDS utilizing a chronic continuous drug delivery paradigm. The goal ... -
Early Prevention of Severe Neurodevelopmental Behavior Disorders: An Integration
(Taylor and Francis, 2012-01-01)There is a very substantial literature over the past 50 years on the advantages of early detection and intervention on the cognitive, communicative, and social-emotional development of infants and toddlers at risk for ... -
Diet Quality of Overweight and Obese Adults with Intellectual and Developmental Disbilities as Measured by the Healthy Eating Index-2005
(Springer Verlag, 2013-12-01)BACKGROUND: Little research has been conducted to examine diet quality of overweight and obese adults with intellectual and developmental disabilities (IDD) in the United States. The purpose of this study was to determine ... -
Prenatal DHA Supplementation and Infant Attention
(Nature Publishing Group, 2016-06-30)Background Results of randomized trials on the effects of prenatal docosahexaenoic acid (DHA) on infant cognition are mixed, but most trials have used global standardized outcomes, which may not be sensitive to effects ... -
Dietary predictors of visceral adiposity in overweight young adults
(Cambridge University Press, 2010-06)The purpose of the present study was to determine the dietary predictors of visceral adipose tissue (VAT) area in overweight young adults. A total of 109 young adults (fifty males and fifty-nine females) ate ad libitum in ... -
Teaching Individuals to Signal for Assistance in a Timely Manner
(Wiley, 2012-11)The study describes the adaptive-switch performances of 8 adults with severe multiple impairments. Each was given a series of progressively more difficult discrimination tasks that, if solved, would require the participant ... -
Adapted digital music players for individuals with severe impairments
(Wiley, 2011-05)Portable music production devices, such as radios, cassette players and MP3 players have characteristics that make them less than ideal for teaching the cause-and-effect relationships that would enable children and adults ... -
Force-plate quantification of progressive behavioral deficits in the R6/2 mouse model of Huntington’s disease
(Elsevier, 2009-08-24)The R6/2 mouse is a popular model of Huntington’s disease (HD) because of its rapid progression and measurable behavioral phenotype. Yet current behavioral phenotyping methods are usually univariate (e.g., latency to fall ... -
The Role of Maternal Gesture Use in Speech Use by Children with Fragile X Syndrome
(American Speech-Language-Hearing Association, 2014-05-01)Purpose--The purpose of this study was to investigate how maternal gesture relates to speech production by children with fragile X syndrome (FXS). Method--Participants were 27 young children with FXS (23 boys, 4 girls) and ... -
Risk Factors for Self-Injury, Aggression, and Stereotyped Behavior Among Young Children At Risk for Intellectual and Developmental Disabilities
(American Association on Intellectual and Developmental Disabilities, 2014-07)Before the 1990s, research on the early identification and prevention of severe behavior disorders (SBDs), such as aggression, self-injury, and stereotyped behavior, among young children with intellectual and developmental ... -
Maternal Responsivity Predicts Language Development in Young Children With Fragile X Syndrome
(American Association on Intellectual and Developmental Disabilities, 2010-01)The relationship between early maternal responsivity and later child communication outcomes in young children with fragile X syndrome was investigated. Data were obtained from 55 mother–child dyads over a 36-month period. ... -
Physical Activity Across the Curriculum (PAAC): a randomized controlled trial to promote physical activity and diminish overweight and obesity in elementary school children
(Elsevier, 2009-08-06)Objective Physical Activity Across the Curriculum (PAAC) was a three-year cluster randomized controlled trial to promote physical activity and diminish increases in overweight and obesity in elementary school ... -
Development of the Communication Complexity Scale
(American Association on Intellectual and Developmental Disabilities, 2012-02)Accurate description of an individual's communication status is critical in both research and practice. Describing the communication status of individuals with severe intellectual and developmental disabilities is difficult ... -
Matching Variables for Research Involving Youth with Down Syndrome: Leiter-R versus PPVT-4
(Elsevier, 2013-12-18)Much of what is known about the cognitive profile of Down syndrome (DS) is based on using either receptive vocabulary (e.g., PPTV-4) or nonverbal ability (e.g., Leiter-R) as a baseline to represent cognitive developmental ... -
Establishing a Conditional Signal for Assistance in Teenagers with Blindness
(Elsevier, 2013-03-05)Five teenagers with severe intellectual impairments and no discernible communication skills were enrolled in training to teach a conditional request for assistance using a speech-generating device (SGD). All were either ... -
Innovation of a Reinforcer Preference Assessment with the Difficult to Test
(Elsevier, 2011-03-15)In this study, we continued evaluation of a two-choice preference assessment aimed at identifying a hierarchy of reinforcers for individuals with only one voluntary motor sequence—closing and releasing an adaptive switch. ... -
Targeting neurosteroid synthesis as a therapy for schizophrenia-related alterations induced by early psychosocial stress
(Elsevier, 2015-05-18)Background Cogent evidence has shown that schizophrenia vulnerability is enhanced by psychosocial stress in adolescence, yet the underpinnings of this phenomenon remain elusive. One of the animal models that best capture ...