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    Population Extinction and the Genetics of Adaptation

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    Unckless_2008.pdf (256.9Kb)
    Issue Date
    2008-08
    Author
    Orr, H. Allen
    Unckless, Robert L.
    Publisher
    University of Chicago Press
    Type
    Article
    Article Version
    Scholarly/refereed, publisher version
    Metadata
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    Abstract
    Theories of adaptation typically ignore the effect of environmental change on population size. But some environmental challenges—challenges to which populations must adapt—may depress absolute fitness below 1, causing populations to decline. Under this scenario, adaptation is a race; beneficial alleles that adapt a population to the new environment must sweep to high frequency before the population becomes extinct. We derive simple, though approximate, solutions to the probability of successful adaptation (population survival) when adaptation involves new mutations, the standing genetic variation, or a mixture of the two. Our results show that adaptation to such environmental challenges can be difficult when relying on new mutations at one or a few loci, and populations will often decline to extinction.
    URI
    http://hdl.handle.net/1808/21261
    DOI
    https://doi.org/10.1086/589460
    Collections
    • Molecular Biosciences Scholarly Works [581]
    Citation
    H. Allen Orr and Robert L. Unckless , "Population Extinction and the Genetics of Adaptation.," The American Naturalist 172, no. 2 (August 2008): 160-169.

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    Contact KU ScholarWorks
    785-864-8983
    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    Image Credits
     

     

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