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KU Med Center Dissertations and Theses: Recent submissions
Now showing items 381-400 of 464
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Characteristics associated with comprehensive stool analysis findings in adult integrative medicine patients
(University of Kansas, 2011-12-31)This pilot study explores relationships between clinical and socio-demographic characteristics and abnormal comprehensive stool analysis (CSA) results of patients at the Integrative Medicine Clinic at the University of ... -
MICRO-RNA146B PROMOTES ALVEOLAR PROGENITOR CELL MAINTENANCE THROUGH PREFERENTIAL REGULATION OF STAT3B
(University of Kansas, 2012-08-31)In this research, we have demonstrated that miRNA146b-5p (miR146b) is a hormonally regulated miRNA that participates in the maintenance of mammary alveolar progenitors during pregnancy and lactation by preferential regulation ... -
TESTING A CONCEPTUAL FRAMEWORK FOR SELF- CARE IN PERSONS WITH DIABETES: THE EFFECT OF DEPRESSION
(University of Kansas, 2012-05-31)Diabetes is a major source of morbidity, mortality, and economic expense. Not only do people with diabetes have a higher risk of developing depression, the rate of depression is much higher than in the general population ... -
THE EFFECT OF INTRAWOUND VANCOMYCIN POWDER ON SURGICAL SITE INFECTIONS IN POSTERIOR INSTRUMENTED SPINAL ARTHRODESES
(University of Kansas, 2012-08-31)Summary: We reviewed 371 consecutive patients from Oct. 2008 to Sept. 2011 who underwent posterior instrumented spinal arthrodesis and received intrawound vancomycin powder prior to closure and compared their acute, deep ... -
Exploring Perceptions of the Ability of Student Nurses to Achieve Learning Outcomes in Community-Based Psychiatric Mental Health Clinical Settings
(University of Kansas, 2012-08-31)The purpose of this qualitative descriptive study was to investigate how traditional undergraduate baccalaureate (BSN) student nurses and their faculty perceive students' ability to achieve learning outcomes in community-based ... -
THE EFFECTS OF HIV INFECTION ON THE EXPRESSION OF THE DRUG EFFLUX PROTEINS P-GLYCOPROTEIN AND BREAST CANCER RESISTANCE PROTEIN IN A HUMAN INTESTINE MODEL
(University of Kansas, 2012-08-31)Background: Emerging evidence suggests poor antiretroviral penetration within human gastrointestinal (GI) tissues may contribute to HIV persistence within reservoirs despite effective therapy. We hypothesize that HIV ... -
Association of Diagnostic Blood Loss from Phlebotomy and Hospital-Acquired Anemia During Admission with Acute Myocardial Infarction
(University of Kansas, 2010-12-31)Introduction: Acute, hospital-acquired anemia (HAA) during admission with AMI is associated with higher mortality and worse health status, and often occurs in the absence of recognized bleeding. Diagnostic blood loss from ... -
Infected Lives: A Heideggerian Phenomenological Study of Young African American Human Immunodeficiency Virus-Positive Women
(University of Kansas, 2012-05-31)Human Immunodeficiency Virus (HIV) infection continues to be a significant health concern for African American women, as they comprise 64% of HIV-positive women in the US. The purpose of this Heideggerian phenomenological ... -
The Effect of Nursing Faculty Presence on Students' Level of Anxiety, Self-Confidence, and Clinical Performance During a Clinical Simulation Experience
(University of Kansas, 2012-05-31)Nursing schools design their clinical simulation labs based upon faculty's perception of the optimal environment to meet the students' learning needs, other programs' success with integrating high-tech clinical simulation, ... -
Cortical Plasticity and Behavioral Recovery Following Focal Lesion to Primary Motor Cortex in Adult Rats
(University of Kansas, 2012-05-31)Acquired brain injuries, such as ischemic stroke and traumatic brain injury, are the leading causes of physical disabilities. Previously, scientists have shown that damage of the primary motor cortex induced neural plasticity ... -
The role of the rhesus macaque (macaca mulatta) apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3) in lentiviral replication and persistence
(University of Kansas, 2012-05-31)SHIV infections in rhesus macaques have been used to extensively study accessory proteins of HIV-1 involved in pathogenesis as well as in vaccine development. All primate lentiviruses encode for a Vif (virion infectivity ... -
Identification, Exploitation and Manipulation of BRCA1-Dependent DNA Double-Strand Break and Interstrand Crosslink Repair in Breast and Ovarian Cancer Therapy
(University of Kansas, 2012-05-12)Expression of functional breast cancer susceptibility gene 1 (BRCA1) in human cancers is associated with resistance to platinum-based chemotherapeutics and poly(ADP-ribose) polymerase (PARP) inhibitors. BRCA1 is a nuclear ... -
Student Perceptions of the Observer Role Play Experiences in the Implementation of a High Fidelity Patient Simulation in Bachelor's Degree Nursing Programs
(University of Kansas, 2012-05-31)Research has shown that high fidelity patient simulation (HFPS) experiences can improve critical thinking, increase students' self-confidence, improve psychomotor skills, advance communication skills, and increase awareness ... -
Mechanosensitivity and Neural Adaptation in Human Somatosensory System
(University of Kansas, 2012-05-31)Magnetoencephalography (MEG) was utilized to characterize the adaptation in the somatosensory cortical network due to repeated cutaneous tactile stimulation applied unilaterally on the face and hand using a custom-built ... -
EFFECTS OF THE NOVEL ATYPICAL ANTIPSYCHOTIC, ARIPIPRAZOLE, ON RATS PERFORMING SIGNALED AND UNSIGNALED TEMPORAL DISCRIMINATION TASKS.
(University of Kansas, 2012-05-31)In contrast to other atypical antipsychotics, aripiprazole (ARZ) acts as a partial agonist, rather than an antagonist, at dopamine D2 receptors (Burris et al, 2002; Jordan et al, 2002). This unique pharmacology is thought ... -
Force Amplitude Modulation of Tongue and Hand Movements
(University of Kansas, 2011-12-31)Rapid, precise movements of the hand and tongue are necessary to complete a wide range of tasks in everyday life. However, the understanding of normal neural control of force production is limited, particularly for the ... -
USE OF DRUG ELUTING STENTS AS A FUNCTION OF PREDICTED BENEFIT: CLINICAL AND ECONOMIC IMPLICATIONS OF CURRENT PRACTICE
(University of Kansas, 2011-12-31)Background: Benefits of drug-eluting stents (DES) in percutaneous coronary intervention (PCI) are greatest in those at the highest risk of target vessel revascularization (TVR). While DES reduce restenosis, they cost more ... -
The interaction of ELKS with Ca2+ channel β subunits may contribute to active zone organization
(University of Kansas, 2011-12-31)The cytoskeletal matrix of the active zone (CAZ) and synaptic voltage-dependent calcium channels (VDCCs) are both required for the organization and regulation of synaptic vesicle release. Here we report a novel interaction ... -
Structural basis of inter-domain electron transfer in Ncb5or, a redox enzyme implicated in diabetes and lipid metabolism
(University of Kansas, 2011-12-31)NADH cytochrome b5 oxidoreductase (Ncb5or) is a multi-domain redox enzyme found in all animal tissues and associated with the endoplasmic reticulum (ER). Ncb5or contains (from N-terminus to C terminus) a novel N-terminal ... -
THE EXPERIENCE OF NURSING STUDENT FAILURE AND SUCCESS: A PHENOMENOLOGICAL INQUIRY
(University of Kansas, 2011-12-31)Abstract Associate degree nursing programs are the primary avenues for basic nursing education in the nation. Nursing schools thought out the United States are concerned about retaining students and have implemented various ...