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Crystallization and preliminary X-ray diffraction studies of d(ACGTAGCTACGT)2:[actinomycin D, (echinomycin)2] and d(ACGTAGCTACGT)2: [actinomycin D, (triostin A)2] complexes
dc.contributor.author | Takusagawa, Hana L. | |
dc.contributor.author | Takusagawa, Fusao | |
dc.date.accessioned | 2015-03-23T20:54:17Z | |
dc.date.available | 2015-03-23T20:54:17Z | |
dc.date.issued | 2000-01-01 | |
dc.identifier.citation | Takusagawa, Hana L.; Takusagawa, Fusao. (2000). "Crystallization and preliminary X-ray diffraction studies of d(ACGTAGCTACGT)2:[actinomycin D, (echinomycin)2] and d(ACGTAGCTACGT)2: [actinomycin D, (triostin A)2] complexes." Acta Crystallographica D, 56(3):344-347. http://www.dx.doi.org/10.1107/S0907444999016790. | en_US |
dc.identifier.issn | 0365-110X | |
dc.identifier.uri | http://hdl.handle.net/1808/17177 | |
dc.description | This is the publisher's version, also available electronically from http://scripts.iucr.org/cgi-bin/paper?S0907444999016790. | en_US |
dc.description.abstract | A DNA-multiple drug complex, d(ACGTAGCTACGT)2:[actinomycin D, (echinomycin)2] has been crystallized. The crystals belong to the monoclinic space group C2, with unit-cell parameters a = 85.6, b = 72.8, c = 56.6 Å, [beta] = 101.5° at 93 K and Z = 8. The crystal diffracted to 3.0 Å resolution along the DNA fiber axis and to 3.5 Å resolution in other directions. The Patterson maps indicate that all complexes in the crystal are oriented along their helical axes in the [10\bar 1] direction. | en_US |
dc.publisher | International Union of Crystallography | en_US |
dc.subject | DNA-drug complexes | en_US |
dc.subject | d(ACGTAGCTACGT)2 | en_US |
dc.subject | actimonycin | en_US |
dc.subject | echinomycin | en_US |
dc.subject | triostin A. | en_US |
dc.title | Crystallization and preliminary X-ray diffraction studies of d(ACGTAGCTACGT)2:[actinomycin D, (echinomycin)2] and d(ACGTAGCTACGT)2: [actinomycin D, (triostin A)2] complexes | en_US |
dc.type | Article | |
kusw.kuauthor | Takusagawa, Hana L. | |
kusw.kuauthor | Takusagawa, Fusao | |
kusw.kudepartment | Molecular Biosciences | en_US |
dc.identifier.doi | 10.1107/S0907444999016790 | |
kusw.oaversion | Scholarly/refereed, publisher version | |
kusw.oapolicy | This item does not meet KU Open Access policy criteria. | |
dc.rights.accessrights | openAccess |