Crystallization and preliminary X-ray diffraction studies of d(ACGTAGCTACGT)2:[actinomycin D, (echinomycin)2] and d(ACGTAGCTACGT)2: [actinomycin D, (triostin A)2] complexes

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Issue Date
2000-01-01Author
Takusagawa, Hana L.
Takusagawa, Fusao
Publisher
International Union of Crystallography
Type
Article
Article Version
Scholarly/refereed, publisher version
Metadata
Show full item recordAbstract
A DNA-multiple drug complex, d(ACGTAGCTACGT)2:[actinomycin D, (echinomycin)2] has been crystallized. The crystals belong to the monoclinic space group C2, with unit-cell parameters a = 85.6, b = 72.8, c = 56.6 Å, [beta] = 101.5° at 93 K and Z = 8. The crystal diffracted to 3.0 Å resolution along the DNA fiber axis and to 3.5 Å resolution in other directions. The Patterson maps indicate that all complexes in the crystal are oriented along their helical axes in the [10\bar 1] direction.
Description
This is the publisher's version, also available electronically from http://scripts.iucr.org/cgi-bin/paper?S0907444999016790.
ISSN
0365-110XCollections
Citation
Takusagawa, Hana L.; Takusagawa, Fusao. (2000). "Crystallization and preliminary X-ray diffraction studies of d(ACGTAGCTACGT)2:[actinomycin D, (echinomycin)2] and d(ACGTAGCTACGT)2: [actinomycin D, (triostin A)2] complexes." Acta Crystallographica D, 56(3):344-347. http://www.dx.doi.org/10.1107/S0907444999016790.
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