Chemistry Dissertations and Theses: Recent submissions
Now showing items 41-60 of 335
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ADENYLATION AND TAILORING ACTIVITIES IN THE NONRIBOSOMAL PEPTIDE SYNTHESIS OF THE SIDEROPHORE PYOCHELIN
(University of Kansas, 2018-12-31)Pathogenic bacteria are becoming increasingly resistant to antibiotics. In response to this alarming trend, the scientific community must determine therapeutic targets. Essential nutrients, such as iron, are necessary for ... -
Stereoselective Additions to Cyclopropenes
(University of Kansas, 2018-05-31)This thesis concerns strain-release driven stereoselective addition reactions to cyclopropenes leading to the synthesis of medium-sized 8-membered 1,5-dioxocane ring structures, optically active cyclopropylboronates, and ... -
Neurochemical methods for the sub-second measurement of neurotransmitter release
(University of Kansas, 2017-12-31)This dissertation is a compilation of work on the development of new methods and models to study neurochemical changes. Using fast-scan cyclic voltammetry to measure electroactive species is the common theme that ties these ... -
Measurements of neurotransmitter release in animal models of the central nervous system using fast scan cyclic voltammetry
(University of Kansas, 2017-12-31)This dissertation is a compilation of the work we have done in the past five years using fast-scan cyclic voltammetry in model organisms to solve biological problems. In this work, we use fast-scan cyclic voltammetry to ... -
MS/MS ANALYSIS OF IgG3 DISULFIDE BONDS AND DEVELOPMENT OF A NOVEL TOOL TO ASSESS ALGORITHMS THAT ASSIGN GLYCOPEPTIDE CID DATA
(University of Kansas, 2017-12-31)With the rapidly increasing use of proteins as biotherapeutics to treat diseases, the characterization of these large molecules using mass spectrometry has become a highly attractive field of research. A particular area ... -
Synthesis of Cyclopropane-Fused 1,5-Diazocin-2-ones via Metal-Templated Intramolecular Addition of Nitrogen Nucleophiles to Pre-Generated Cyclopropenes
(University of Kansas, 2018-08-31)This thesis is concerned with the development of methods by which to access compounds possessing the 3,4-cyclopropane-annulated 1,5-diazocin-2-one scaffold. The methods described herein are based on the intramolecular ... -
Graphene Oxide Microelectrodes for Detection of Hydrogen Peroxide
(University of Kansas, 2017-05-31)Hydrogen peroxide is a membrane-permeable reactive oxygen species (ROS) and a neuromodulator. Here, we enhanced the electrochemical detection of hydrogen peroxide by modifying a carbon-fiber microelectrode by dip-coating ... -
The fusion curves for the systems ammonia-propyl alcohols, ammonia-butyl alcohols
(University of Kansas, 1929)Baume and Perrot used the Phase law method to investigate the system CH3OH + NH3. Broderson used the same method with the system C2H5OH + NH3. Baume and Perrot found that the compound CH3.OH.NH3 was formed in the ammonia ... -
Some studies of binary and ternary systems of nitrates in anhydrous acetic acid
(University of Kansas, 1935) -
On the constitution of disubstituted isothiohydantions
(University of Kansas, 1930) -
The anodic oxidation of aluminum in liquid ammonia
(University of Kansas, 1951) -
The reaction of Reissert compounds with Grignard reagents
(University of Kansas, 1952) -
Microfluidic Digital ELISA towards Single Cell Analysis
(University of Kansas, 2017-12-31)Cell-to-cell heterogeneity predicts a multitude of functions for homeostasis and development of disease states. These minute variations can make a massive impact in understanding the main components involved in a disease ... -
The preparation of pyridine dicarboxylic acids by ozone oxidation and the preparation of fluorine-containing medicinals
(University of Kansas, 1950) -
The reaction of sodium azide with ethylene sulfides, ethylenimines and trimethylene oxide
(University of Kansas, 1952) -
Neurochemical Investigation of Locally Induced Epilepsy and Subsequent Oxidative Damage Using Microdialysis Sampling
(University of Kansas, 2017-05-31)The goal of this research was to develop and understand an anesthetized, multiple-seizure rat model for local epilepsy. Local seizures are not as well understood as global seizures due to their specificity and unpredictability. ... -
Investigation of the Interactions between LOV Domains by Spectroscopic Techniques
(University of Kansas, 2017-12-31)Plants have adapted a variety of methods necessary for their survival such as stomatal opening and closing, plant growth, and photosynthesis. In order to regulate these processes, plants rely on sensing sunlight in their ... -
The synthesis of organic medicinals containing fluorine
(University of Kansas, 1950) -
The electrochemistry of elements of the aluminum family in liquid ammonia
(University of Kansas, 1951) -
Synthesis and properties of the possible isomeric mono-chlor, mono-iodo-toluenes
(University of Kansas, 1927)