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KU ScholarWorks: Recent submissions
Now showing items 1181-1200 of 29499
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Noninvasive Brain Delivery and Efficacy of BDNF to Stimulate Neuroregeneration and Suppression of Disease Relapse in EAE Mice
(American Chemical Society, 2019-12-17)The number of FDA-approved protein drugs (biologics), such as antibodies, antibody–drug conjugates, hormones, and enzymes, continues to grow at a rapid rate; most of these drugs are used to treat diseases of the peripheral ... -
Oxidative Cyclization of Sulfamates onto Pendant Alkenes
(American Chemical Society, 2020-01-13)This communication discloses the first examples of aza-Wacker cyclizations of sulfamate esters. Within the realm of related cyclization reactions, this protocol is differential in that it forms six-membered rings in good ... -
Engineering peptide-polymer hybrids for targeted repair and protection of cervical lesions
(Frontiers Media, 2022-11-25)By 2060, nearly 100 million people in the U.S. will be over age 65 years. One-third of these older adults will have root caries, and nearly 80% will have dental erosion. These conditions can cause pain and loss of tooth ... -
Texas Senate Bill 8 significantly reduced travel to abortion clinics in Texas
(Frontiers Media, 2023-03-20)The Dobbs v. Jackson decision by the United States Supreme Court has rescinded the constitutional guarantee of abortion across the United States. As a result, at least 13 states have banned abortion access with unknown ... -
Young athlete's attitudes toward female sport participation
(University of Kansas, 1984-05-31) -
Anxiety and Depression in Autistic College Students: The Freshman Survey Results
(Springer, 2023-03-06)Objective Mental health among undergraduate students is a growing concern in higher education, but relatively little is known about the mental health of autistic college students. In order to better understand the unique ... -
Effects of carnosine on the embryonic development and TiO2 nanoparticles-induced oxidative stress on Zebrafish
(Frontiers Media, 2023-03-23)Oxidative stress is due to an unbalance between pro-oxidants, such as reactive oxygen (ROS) and nitrogen (RNS) species, and antioxidants/antioxidant system. Under physiological conditions these species are involved in ... -
Editorial Perspective: Maximising the benefits of intervention research for children and young people with developmental language disorder (DLD) – a call for international consensus on standards of reporting in intervention studies for children with and at risk for DLD
(Wiley, 2022-09-20)Current methods for reporting interventions do not allow key questions of importance to practitioners, service providers, policy-makers and people with DLD to be answered, and hence limit the implementation of effective ... -
Challenges in the Development of Intravenous Neurokinin-1 Receptor Antagonists: Results of a Safety and Pharmacokinetics Dose-Finding, Phase 1 Study of Intravenous Fosnetupitant
(Wiley, 2022-10-20)Oral NEPA is the fixed-combination antiemetic comprising netupitant (neurokinin-1 receptor antagonist [NK1RA]) and palonosetron (5-hydroxytryptamine-3 receptor antagonist [5-HT3 RA]). Intravenous (IV) NEPA, containing ... -
Engineered Peptides Enable Biomimetic Route for Collagen Intrafibrillar Mineralization
(MDPI, 2023-03-28)Overcoming the short lifespan of current dental adhesives remains a significant clinical need. Adhesives rely on formation of the hybrid layer to adhere to dentin and penetrate within collagen fibrils. However, the ability ... -
The oldest known bat skeletons and their implications for Eocene chiropteran diversification
(Public Library of Science, 2023-04-12)The Fossil Lake deposits of the Green River Formation of Wyoming, a remarkable early Eocene Lagerstätte (51.98 ±0.35 Ma), have produced nearly 30 bat fossils over the last 50 years. However, diversity has thus far been ... -
The networked micro-decision context: A new lens on transformative urban governance
(BMC, 2023-04-12)Recent large-scale societal disruptions, from the COVID-19 pandemic to intensifying wildfires and weather events, reveal the importance of transforming governance systems so they can address complex, transboundary, and ... -
Coupled Lattice Boltzmann Modeling Framework for Pore-Scale Fluid Flow and Reactive Transport
(American Chemical Society, 2023-04-03)In this paper, we propose a modeling framework for pore-scale fluid flow and reactive transport based on a coupled lattice Boltzmann model (LBM). We develop a modeling interface to integrate the LBM modeling code parallel ... -
Correlation between Lignin–Carbohydrate Complex Content in Grass Lignins and Phenolic Aldehyde Production by Rapid Spray Ozonolysis
(American Chemical Society, 2022-12-19)We provide strong evidence that the amounts of phenolic aldehydes (vanillin and p-hydroxybenzaldehyde, pHB) selectively released during rapid ozonolysis of grass lignins are correlated with the unsubstituted aryl carbons ... -
Deconvoluting Kinetic Rate Constants of Catalytic Substrates from Scanning Electrochemical Approach Curves with Artificial Neural Networks
(American Chemical Society, 2022-11-15)Extracting information from experimental measurements in the chemical sciences typically requires curve fitting, deconvolution, and/or solving the governing partial differential equations via numerical (e.g., finite element ... -
Evaluation of Latex Immunoturbidimetric Assay Thresholds and HIT in Cardiothoracic Surgery
(SAGE Publications, 2023-04-17)Background Heparin-induced thrombocytopenia (HIT) is a common differential diagnosis in cardiothoracic surgery. The latex immunoturbidimetric assay (LIA) is an enhanced immunoassay that has recently been introduced for ... -
Status of corporate health programs and qualifications of program directors in the Association for Fitness in Business
(University of Kansas, 1984-05-31)