Oxidative Cyclization of Sulfamates onto Pendant Alkenes

Shinde, Anand H.; Sathyamoorthi, Shyam

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Issue Date

2020-01-13

Author

Shinde, Anand H.

Sathyamoorthi, Shyam

Publisher

American Chemical Society

Type

Article

Article Version

Scholarly/refereed, author accepted manuscript

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Abstract

This communication discloses the first examples of aza-Wacker cyclizations of sulfamate esters. Within the realm of related cyclization reactions, this protocol is differential in that it forms six-membered rings in good yield and uses catalytic amounts of palladium(0) rather than palladium(II) salts. These reactions scale well, and their products are demonstrated to be valuable synthetic intermediates.

Description

This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright © 2020 American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.orglett.9b04448.

Citation

Shinde, A. H., & Sathyamoorthi, S. (2020). Oxidative Cyclization of Sulfamates onto Pendant Alkenes. Organic letters, 22(3), 896–901. https://doi.org/10.1021/acs.orglett.9b04448

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