Molecular Biosciences Dissertations and Theses: Recent submissions
Now showing items 41-60 of 270
-
A study of the interrelationships existing between Bacillus cereus, Bacillus mycoides and Bacillus anthracis
(University of Kansas, 1957) -
Analysis of the Structure of Phosphorylase Kinase by Mass Spectrometry
(University of Kansas, 2016-12-31)Phosphorylase Kinase (PhK) is a large, 1.3 MDa, regulatory enzyme in the glycogenolysis cascade, made up by four copies each of four different subunits, α, β, γ, and δ, giving 325 kDa of unique sequence. Three of the four ... -
Some studies of antigenic properties of Escherichia coli bacteriophage
(University of Kansas, 1930) -
Inhibition and Allosteric Signaling of Transcription Activation by Bacterial AraC Family Activator Proteins
(University of Kansas, 2016-12-31)AraC family transcriptional activators are defined by a 100-amino acid DNA-binding domain (DBD) containing two DNA binding helix-turn-helix (HTH) motifs. My research focused on three AraC family proteins: RhaR (activator ... -
Gene Expression and Introgression of Two Genes Implicated in Behavioral Reproductive Isolation between Drosophila simulans and D. sechellia
(University of Kansas, 2016-12-31)Reproductive isolation maintains species barriers and can cause population divergence. Pre-mating isolation prevents courtship between species and can be caused by changes in gene expression resulting in sex- and ... -
HSV-1 ICP0-MEDIATED IMPAIRMENT OF HOST INTRINSIC AND INNATE IMMUNE FACTORS
(University of Kansas, 2014-08-31)Understanding mechanisms viruses use to evade the immune system and to persist within its host, is of crucial relevance in controlling, preventing and treating HSV-1-associated diseases. As reviewed in this dissertation, ... -
Computational approaches to identify small-molecule inhibitors of non-traditional drug targets
(University of Kansas, 2015-08-31)Non-traditional targets for therapeutic intervention are those proteins that have not evolved to bind small molecules, but have instead evolved to bind other macromolecules. Such targets include protein–protein interaction ... -
Mining Evolutionary Data to Reveal the Layered Architecture of Protein Function
(University of Kansas, 2014-08-31)Revolutionary advances in sequencing technology have dramatically expanded the set of known, naturally-occurring protein sequences. Protein sequences arise from an evolutionary process and during evolution proteins experience ... -
Cytoplasmic vs. Nuclear RNAi in Caenorhabditis elegans
(University of Kansas, 2014-08-31)ABSTRACT Experimentally and/or intrinsically delivered dsRNAs can trigger complex set of mechanisms, acting in multiple cell compartments and tissues throughout developmental time. Several methods are available for effective ... -
Crosstalk, Network Dynamics, and the Evolution of Signaling
(University of Kansas, 2014-12-31)Cells have developed networks of interacting proteins to process information about their environment and respond appropriately to stimuli. Reversible post-translational modifications alter the functionality of these proteins, ... -
The Regulation of Musashi RNA Binding Proteins and the Implications for Cancer Therapy
(University of Kansas, 2015-12-31)RNA-binding protein and stem cell regulator, Musashi-1 (MSI1) is overexpressed in a broad range of human cancers and associated with poor clinical outcome. MSI1 encourages tumorigenesis by promoting Notch and Wnt signaling, ... -
Studies on Endamoeba histolytica, its accompanying bacteria, and Blastocystis hominis
(University of Kansas, 1932) -
The carbon monoxide content of the blood of garage workers
(University of Kansas, 1932) -
Macroglobulin complement-related, coracle and Neuroglian are required for Drosophila egg morphogenesis
(University of Kansas, 2016-05-31)Morphogenesis, along with cell growth and differentiation are crucial processes that define the body plan of an organism. Morphogenetic movements such as neural tube formation, gastrulation and organogenesis are accomplished ... -
A study of the chlorination of milk
(University of Kansas, 1929) -
Studies in bacterial association
(University of Kansas, 1931) -
Cytological and bacteriological aspects of refrigerator slime
(University of Kansas, 1930) -
Studies on pernicious anemia
(University of Kansas, 1929) -
Lantibiotic Smb: Characterization of the immunity protein, identification of a novel receptor-like protein, and a new perspective on regulation
(University of Kansas, 2014-05-31)Dental caries, commonly known as tooth decay, is a chronic disease that develops slowly and requires formation of biofilm on tooth surfaces, commonly known as dental plaque. Dental plaque is a highly complex multispecies ...