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Now showing items 401-420 of 918

    • A modest proposal in four parts 

      Turnbull, H. Rutherford, III (2011-12-27)
    • Predicting suitable environments and potential occurrences for coelacanths (Latimeria spp.) 

      Owens, Hannah L.; Bentley, Andrew C.; Peterson, A. Townsend (Springer Verlag, 2011)
      Extant coelacanths (Latimeria chalumnae) were first discovered in the western Indian Ocean in 1938; in 1998, a second species of coelacanth, Latimeria menadoensis, was discovered off the north coast of Sulawesi, Indonesia, ...
    • Understanding verbal fluency in healthy aging, Alzheimer’s disease, and Parkinson’s disease 

      McDowd, Joan M.; Hoffman, Lesa; Rozek, Ellen Kathryn; Lyons, Kelly E.; Pahwa, Rajesh; Burns, Jeffrey M.; Kemper, Susan (Elsevier, 2011)
      • Objective: Verbal fluency measures are frequently part of batteries designed to assess executive function, but are also used to assess semantic processing ability or word knowledge. The goal of the present study was to ...
    • Cyclopropylamine inactivation of cytochromes P450: Role of metabolic intermediate complexes 

      Cerny, Matthew A.; Hanzlik, Robert P. (Elsevier, 2005-04-15)
      The inactivation of cytochrome P450 enzymes by cyclopropylamines has been attributed to a mechanism involving initial one-electron oxidation at nitrogen followed by scission of the cyclopropane ring leading to covalent ...
    • Molecular Basis for the High Affinity Binding and Stabilization of Firefly Luciferase by PTC124 

      Auld, Douglas S.; Lovell, Scott; Thorne, Natasha; Lea, Wendy A.; Maloney, David J.; Shen, Min; Rai, Ganesha; Battaile, Kevin P.; Thomas, Craig J.; Simeonov, Anton; Hanzlik, Robert P.; Inglese, James (National Academy of Sciences, 2010-03-16)
      Firefly luciferase (FLuc), an ATP-dependent bioluminescent reporter enzyme, is broadly used in chemical biology and drug discovery assays. PTC124 (Ataluren; (3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid) discovered ...
    • Longitudinal change in language production: Effects of aging and dementia on grammatical complexity and semantic content 

      Kemper, Susan; Thompson, Marilyn; Marquis, Janet (American Psychological Association, 2001-12)
      Mixed modeling was used to examine longitudinal changes in linguistic ability in healthy older adults and older adults with dementia. Language samples, vocabulary scores, and digit span scores were collected annually from ...
    • The structure of verbal abilities in young and older adults 

      Kemper, Susan; Sumner, Aaron (American Psychological Association, 2001-06)
      Four language sample measures as well as measures of vocabulary, verbal fluency, and memory span were obtained from a sample of young adults and a sample of older adults. Factor analysis was used to analyze the structure ...
    • Age differences in sentence production 

      Kemper, Susan; Herman, Ruth E.; Lian, Cindy (Oxford University Press, 2003-09)
      Two experiments have been completed using experimental techniques to study language production under controlled conditions. In Experiment 1, young and older adults were given two, three, or four words and asked to compose ...
    • The Costs of Doing Two Things at Once for Young and Older Adults: Talking while Walking, Finger Tapping, and Ignoring Speech or Noise 

      Kemper, Susan; Herman, Ruth E.; Lian, Cindy (American Psychological Association, 2003-06)
      Young and older adults provided language samples in response to questions while walking, finger tapping, and ignoring speech or noise. The language samples were scored on 3 dimensions: fluency, complexity, and content. The ...
    • Sentence production by younger and older adults in controlled contexts 

      Kemper, Susan; Herman, Ruth E.; Liu, Chiung-Ju (Oxford University Press, 2004-09)
      In this experiment we compared young and older adults' abilities to produce complex sentences under controlled conditions. We asked participants to memorize sentence stems differing in syntactical complexity and then to ...
    • Eye fixation patterns of high and low span young and older adults: Down the garden path and back again 

      Kemper, Susan; Crow, Angela; Kemtes, Karen A. (American Psychological Association, 2004-03)
      Young and older adults' eye fixations were monitored as they read sentences with temporary ambiguities such as "The experienced soldiers warned about the dangers conducted the midnight raid." Their fixation patterns were ...
    • Different effects of dual task demands on the speech of young and older adults 

      Kemper, Susan; Herman, Ruth E.; Nartowicz, Jennifer (Taylor & Francis (Psychology Press), 2005-12)
      Young and older adults provided language samples in response to elicitation questions while concurrently performing 3 different tasks. The language samples were scored on three dimensions: fluency, grammatical complexity, ...
    • Revealing language deficits following stroke: the cost of doing two things at once 

      Kemper, Susan; McDowd, Joan M.; Pohl, Patricia; Herman, Ruth E.; Jackson, Susan (Taylor & Francis (Psychology Press), 2006-01)
      The costs of doing two things were assessed for a group of healthy older adults and older adults who were tested at least 6 months after a stroke. A baseline language sample was compared to language samples collected while ...
    • Eye movements of young and older adults while reading with distraction 

      Kemper, Susan; McDowd, Joan M.; Kramer, Arthur F. (American Psychological Association, 2006-03)
      The authors used eye-tracking technology to examine young and older adults' online performance in the reading in distraction paradigm. Participants read target sentences and answered comprehension questions following each ...
    • Eye movements of young and older adults during reading 

      Kemper, Susan; Liu, Chiung-Ju (American Psychological Association, 2007-03)
      The eye movements of young and older adults were tracked as they read sentences varying in syntactic complexity. In Experiment 1, cleft object and object relative clause sentences were more difficult to process than cleft ...
    • Automatic measurement of propositional idea density from part-of-speech tagging 

      Brown, Cati; Snodgrass, Tony; Kemper, Susan; Herman, Ruth E.; Covington, Michael A. (Springer, 2008-05)
      The Computerized Propositional Idea Density Rater (CPIDR, pronounced “spider”) is a computer program that determines the propositional idea density (P-density) of an English text automatically on the basis of partof-speech ...
    • The effects of aging and dual task performance on language production 

      Kemper, Susan; Schmalzried, RaLynn Cheri; Herman, Ruth E.; Leedahl, Skye N.; Mohankumar, Deepthi (Taylor & Francis (Psychology Press), 2009-05)
      A digital pursuit rotor task was used to measure dual task costs of language production by young and older adults. After training on the pursuit rotor, participants were asked to track the moving target while providing a ...
    • Aging and the vulnerability of speech to dual task demands 

      Kemper, Susan; Schmalzried, RaLynn Cheri; Hoffman, Lesa; Herman, Ruth E. (American Psychological Association, 2010-12)
      Tracking a digital pursuit rotor task was used to measure dual task costs of language production by young and older adults. Tracking performance by both groups was affected by dual task demands: time on target declined and ...
    • The Effects of Varying Task Priorities on Language Production by Young and Older Adults 

      Kemper, Susan; Schmalzried, RaLynn Cheri; Herman, Ruth E.; Mohankumar, Deepthi (Taylor & Francis, 2011-02)
      The present study compared how varying task priorities affected young and older adults' language production. Both young and older adults responded to monetary incentives to vary their performance when simultaneously talking ...
    • Tracking Talking: Dual Task Costs of Planning and Producing Speech for Young versus Older Adults 

      Kemper, Susan; Hoffman, Lesa; Schmalzried, RaLynn Cheri; Herman, Ruth E.; Kieweg, Douglas (Taylor & Francis (Psychology Press), 2011-05)
      A digital pursuit rotor was used to monitor speech planning and production costs by time-locking tracking performance to the auditory wave form produced as young and older adults were describing someone they admire. The ...