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Epithelial cell polarity and cell junctions in drosophila
dc.contributor.author | Tepass, Ulrich | |
dc.contributor.author | Tanentzapf, Guy | |
dc.contributor.author | Ward, Robert E., IV | |
dc.contributor.author | Fehon, Richard G. | |
dc.date.accessioned | 2005-09-30T12:52:56Z | |
dc.date.available | 2005-09-30T12:52:56Z | |
dc.date.issued | 2001-12 | |
dc.identifier.citation | Tepass, U, Tanentzapf G, Ward, RE, and Fehon, RG. Epithelial cell polarity and cell junctions in drosophila. Annual Review of Genetics. December 2001. 35(747) : 747-784. | |
dc.identifier.uri | http://hdl.handle.net/1808/674 | |
dc.description.abstract | The polarized architecture of epithelial cells and tissues is a fundamental determinant of animal anatomy and physiology. Recent progress made in the genetic and molecular analysis of epithelial polarity and cellular junctions in Drosophila has led to the most detailed understanding of these processes in a whole animal model system to date. Asymmetry of the plasma membrane and the differentiation of membrane domains and cellular junctions are controlled by protein complexes that assemble around transmembrane proteins such as DE-cadherin, Crumbs, and Neurexin IV, or other cytoplasmic protein complexes that associate with the plasma membrane. Much remains to be learned of how these complexes assemble, establish their polarized distribution, and contribute to the asymmetric organization of epithelial cells. | |
dc.format.extent | 547374 bytes | |
dc.format.mimetype | application/pdf | |
dc.language.iso | en | |
dc.publisher | Annual Review | |
dc.subject | Epithelium | |
dc.subject | Cellular junctions | |
dc.subject | Polarity | |
dc.subject | Cellularization | |
dc.subject | membrane domain | |
dc.title | Epithelial cell polarity and cell junctions in drosophila | |
dc.type | Article | |
dc.rights.accessrights | openAccess |