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Protein Structure Prediction: Is It Useful?
| dc.contributor.author | Zhang, Yang | |
| dc.date.accessioned | 2017-06-08T20:30:30Z | |
| dc.date.available | 2017-06-08T20:30:30Z | |
| dc.date.issued | 2009-04 | |
| dc.identifier.citation | Zhang, Y. (2009). Protein Structure Prediction: Is It Useful? Current Opinion in Structural Biology, 19(2), 145–155. http://doi.org/10.1016/j.sbi.2009.02.005 | en_US |
| dc.identifier.uri | http://hdl.handle.net/1808/24448 | |
| dc.description.abstract | Computationally predicted three-dimensional structure of protein molecules has demonstrated the usefulness in many areas of biomedicine, ranging from approximate family assignments to precise drug screening. For nearly 40 years, however, the accuracy of the predicted models has been dictated by the availability of close structural templates. Progress has recently been achieved in refining low-resolution models closer to the native ones; this has been made possible by combining knowledge-based information from multiple sources of structural templates as well as by improving the energy funnel of physics-based force fields. Unfortunately, there has been no essential progress in the development of techniques for detecting remotely homologous templates and for predicting novel protein structures. | en_US |
| dc.publisher | Elsevier | en_US |
| dc.rights | This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 4.0 (CC BY-NC-ND 4.0), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | en_US |
| dc.title | Protein Structure Prediction: Is It Useful? | en_US |
| dc.type | Article | en_US |
| kusw.kuauthor | Zhang, Yang | |
| kusw.kudepartment | Molecular Biosciences | en_US |
| dc.identifier.doi | 10.1016/j.sbi.2009.02.005 | en_US |
| kusw.oaversion | Scholarly/refereed, author accepted manuscript | en_US |
| kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
| dc.identifier.pmid | PMC2673339 | en_US |
| dc.rights.accessrights | openAccess |
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Except where otherwise noted, this item's license is described as: This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 4.0 (CC BY-NC-ND 4.0), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
