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Research Centers: Recent submissions
Now showing items 81-100 of 241
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Triheptanoin Mitigates Brain ATP Depletion and Mitochondrial Dysfunction in a Mouse Model of Alzheimer’s Disease
(IOS Press, 2020-10-27)Background: Brain energy failure is an early pathological event associated with synaptic dysfunction in Alzheimer’s disease (AD). Thus, mitigation or enhancement of brain energy metabolism may offer a therapeutic avenue. ... -
Nutrient export to groundwater across a land use and historical climate gradient
(2019)Groundwater inputs to streams are important to intermittent stream function and can be a source of nutrients such as nitrogen and phosphorus. The amount of nutrients within groundwater are an important factor for downstream ... -
Variation in Stream Chemistry Across the Kansas Precipitation Gradient
(2019)How do stream order, land use, and stream position within the precipitation gradient across Kansas affect stream chemistry? Land use will drive changes in stream chemistry that are biologically driven (e.g., DOC, NO3-), ... -
Soil Oxygen Dynamics: Patterns and Lessons from Six Years of High Frequency Monitoring
(2019)Soil oxygen (O2) is a fundamental control on terrestrial biogeochemical cycles including processes producing and consuming greenhouse gases (GHG), yet it is rarely measured. Instead, soil O2 is assumed to be proportional ... -
Patterns of soil organic carbon deficit in the Conterminous US
(2018-12-12)Soil organic carbon (SOC) is integral to ecosystem stability, agricultural productivity, and climate regulation. The capacity of soils to stabilize additional SOC is highly uncertain, yet critical to understanding terrestrial ... -
High nitrous oxide fluxes from rice indicate the need to manage water for both long- and short-term climate impacts
(National Academy of Sciences, 2018-09-25)Global rice cultivation is estimated to account for 2.5% of current anthropogenic warming because of emissions of methane (CH4), a short-lived greenhouse gas. This estimate assumes a widespread prevalence of continuous ... -
Seasonal Salinization Decreases Spatial Heterogeneity of Sulfate Reducing Activity
(MDPI, 2019-04-02)Evidence of sulfate input and reduction in coastal freshwater wetlands is often visible in the black iron monosulfide (FeS) complexes that form in iron rich reducing sediments. Using a modified Indicator of Reduction in ... -
Potent modulation of the CepR quorum sensing receptor and virulence in a Burkholderia cepacia complex member using non-native lactone ligands
(Nature Research, 2019-09-17)The Burkholderia cepacia complex (Bcc) is a family of closely related bacterial pathogens that are the causative agent of deadly human infections. Virulence in Bcc species has been shown to be controlled by the CepI/CepR ... -
Reply to Wassmann et al.: More data at high sampling intensity from medium- and intense-intermittently flooded rice farms is crucial
(National Academy of Sciences, 2019-01-22)Here, we briefly respond to critique of our study (1) by Wassmann et al. (2). A detailed response to their letter is available online (edf.org/riceN2O). -
Kansas Fire & Rescue Training Institute Training Methodology: Best Practices for Fire Service Instructors
(University of Kansas, Fire & Rescue Training Institute, 2021-02-03)Until October 2020, Kansas Fire & Rescue Training Institute (KFRTI) had over 300 contract fire instructors registered within the learning management system. This is a large number of instructors to manage and there is no ... -
The complete mitogenome of a South African cryptic species of tadpole shrimp within the Triops granarius (Lucas, 1864) species group
(Taylor & Francis Open Access, 2019-01-22)The complete mitochondrial genome of a cryptic species of tadpole shrimp from South Africa (Accession Number: MG770893) was recovered by low coverage shotgun sequencing. The mitogenome consists of 15,216 bp with a GC content ... -
Diversity in lac Operon Regulation among Diverse Escherichia coli Isolates Depends on the Broader Genetic Background but Is Not Explained by Genetic Relatedness
(American Society for Microbiology, 2019-11-12)Transcription of bacterial genes is controlled by the coordinated action of cis- and trans-acting regulators. The activity and mode of action of these regulators can reflect different requirements for gene products in ... -
Measuring Height Change Around the Periphery of the Greenland Ice Sheet With Radar Altimetry
(Frontiers Media, 2019-06-11)Ice loss measurements around the periphery of the Greenland Ice Sheet can provide key information on the response to climate change. Here we use the excellent spatial and temporal coverage provided by the European Space ... -
CReSIS airborne radars and platforms for ice and snow sounding
(International Glaciological Society, 2019-11-19)This paper provides an update and overview of the Center for Remote Sensing of Ice Sheets (CReSIS) radars and platforms, including representative results from these systems. CReSIS radar systems operate over a frequency ... -
Deciphering Off-Target Effects in CRISPR-Cas9 through Accelerated Molecular Dynamics
(American Chemical Society, 2019-03-07)CRISPR-Cas9 is the state-of-the-art technology for editing and manipulating nucleic acids. However, the occurrence of off-target mutations can limit its applicability. Here, all-atom enhanced molecular dynamics (MD) ... -
A Computational Modeling Approach Predicts Interaction of the Antifungal Protein AFP from Aspergillus giganteus with Fungal Membranes via Its γ-Core Motif
(American Society for Microbiology, 2018-10-03)Fungal pathogens kill more people per year globally than malaria or tuberculosis and threaten international food security through crop destruction. New sophisticated strategies to inhibit fungal growth are thus urgently ... -
Hard rock landforms generate 130 km ice shelf channels through water focusing in basal corrugations
(Nature Research, 2018-11-01)Satellite imagery reveals flowstripes on Foundation Ice Stream parallel to ice flow, and meandering features on the ice-shelf that cross-cut ice flow and are thought to be formed by water exiting a well-organised subglacial ... -
A large impact crater beneath Hiawatha Glacier in northwest Greenland
(American Association for the Advancement of Science, 2018-11-14)We report the discovery of a large impact crater beneath Hiawatha Glacier in northwest Greenland. From airborne radar surveys, we identify a 31-kilometer-wide, circular bedrock depression beneath up to a kilometer of ice. ... -
Structural Basis for Binding of Allosteric Drug Leads in the Adenosine A1 Receptor
(Nature Research, 2018-11-15)Despite intense interest in designing positive allosteric modulators (PAMs) as selective drugs of the adenosine A1 receptor (A1AR), structural binding modes of the receptor PAMs remain unknown. Using the first X-ray structure ... -
High-Throughput Screening for Bacterial Glycosyltransferase Inhibitors
(Frontiers Media, 2018-12-18)The enteropathogenic and enterohemorrhagic Escherichia coli NleB proteins as well as the Salmonella enterica SseK proteins are type III secretion system effectors that function as glycosyltransferase enzymes to ...