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A Nitro Enolate Approach to the Synthesis of 4, 5-Disubstituted-2-Aminoimidazoles. Pilot Library Assembly and Screening for Antibiotic and Antibiofilm Activity

dc.contributor.authorZhaoming, Su
dc.contributor.authorRogers, Steven A.
dc.contributor.authorMcCall, W. Steve
dc.contributor.authorSmith, Alicia C.
dc.contributor.authorRavishankar, Sindhu
dc.contributor.authorMullikin, Trey
dc.contributor.authorMelander, Christian
dc.date.accessioned2015-11-20T23:05:53Z
dc.date.available2015-11-20T23:05:53Z
dc.date.issued2010-04-29
dc.identifier.citationSu, Zhaoming, Steven A. Rogers, W. Steve Mccall, Alicia C. Smith, Sindhu Ravishankar, Trey Mullikin, and Christian Melander. "A Nitroenolate Approach to the Synthesis of 4,5-disubstituted-2-aminoimidazoles. Pilot Library Assembly and Screening for Antibiotic and Antibiofilm Activity." Organic & Biomolecular Chemistry Org. Biomol. Chem. 8.12 (2010): 2814. DOI:10.1039/C001479Fen_US
dc.identifier.urihttp://hdl.handle.net/1808/18973
dc.descriptionThis is the published version. Copyright Royal Society of Chemistryen_US
dc.description.abstractA library of 4,5-disubstituted-2-aminoimidazoles was synthesized using a nitroenolate route and then screened for antibiofilm and antimicrobial activity. These compounds displayed notable biofilm dispersal and planktonic microbicidal activity against various Gram-positive and Gram-negative bacteria.en_US
dc.publisherRoyal Society of Chemistryen_US
dc.titleA Nitro Enolate Approach to the Synthesis of 4, 5-Disubstituted-2-Aminoimidazoles. Pilot Library Assembly and Screening for Antibiotic and Antibiofilm Activityen_US
dc.typeArticle
kusw.kuauthorRogers, Steven A.
kusw.kudepartmentChemistryen_US
dc.identifier.doi10.1039/C001479F
kusw.oaversionScholarly/refereed, publisher version
kusw.oapolicyThis item meets KU Open Access policy criteria.
dc.rights.accessrightsopenAccess


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