A Nitro Enolate Approach to the Synthesis of 4, 5-Disubstituted-2-Aminoimidazoles. Pilot Library Assembly and Screening for Antibiotic and Antibiofilm Activity

Zhaoming, Su; Rogers, Steven A.; McCall, W. Steve; Smith, Alicia C.; Ravishankar, Sindhu; Mullikin, Trey; Melander, Christian

dc.contributor.author	Zhaoming, Su
dc.contributor.author	Rogers, Steven A.
dc.contributor.author	McCall, W. Steve
dc.contributor.author	Smith, Alicia C.
dc.contributor.author	Ravishankar, Sindhu
dc.contributor.author	Mullikin, Trey
dc.contributor.author	Melander, Christian
dc.date.accessioned	2015-11-20T23:05:53Z
dc.date.available	2015-11-20T23:05:53Z
dc.date.issued	2010-04-29
dc.identifier.citation	Su, Zhaoming, Steven A. Rogers, W. Steve Mccall, Alicia C. Smith, Sindhu Ravishankar, Trey Mullikin, and Christian Melander. "A Nitroenolate Approach to the Synthesis of 4,5-disubstituted-2-aminoimidazoles. Pilot Library Assembly and Screening for Antibiotic and Antibiofilm Activity." Organic & Biomolecular Chemistry Org. Biomol. Chem. 8.12 (2010): 2814. DOI:10.1039/C001479F	en_US
dc.identifier.uri	http://hdl.handle.net/1808/18973
dc.description	This is the published version. Copyright Royal Society of Chemistry	en_US
dc.description.abstract	A library of 4,5-disubstituted-2-aminoimidazoles was synthesized using a nitroenolate route and then screened for antibiofilm and antimicrobial activity. These compounds displayed notable biofilm dispersal and planktonic microbicidal activity against various Gram-positive and Gram-negative bacteria.	en_US
dc.publisher	Royal Society of Chemistry	en_US
dc.title	A Nitro Enolate Approach to the Synthesis of 4, 5-Disubstituted-2-Aminoimidazoles. Pilot Library Assembly and Screening for Antibiotic and Antibiofilm Activity	en_US
dc.type	Article
kusw.kuauthor	Rogers, Steven A.
kusw.kudepartment	Chemistry	en_US
dc.identifier.doi	10.1039/C001479F
kusw.oaversion	Scholarly/refereed, publisher version
kusw.oapolicy	This item meets KU Open Access policy criteria.
dc.rights.accessrights	openAccess

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