dc.contributor.author | Yang, Xinmai | |
dc.contributor.author | Jo, Janggun | |
dc.date.accessioned | 2015-10-20T15:38:47Z | |
dc.date.available | 2015-10-20T15:38:47Z | |
dc.date.issued | 2014-11-10 | |
dc.identifier.citation | Yang, Xinmai, and Janggun Jo. "Enhanced Cavitation by Using Two Consecutive Ultrasound Waves at Different Frequencies." Appl. Phys. Lett. Applied Physics Letters 105.19 (2014): 193701. http://dx.doi.org/10.1063/1.4902118 | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/18710 | |
dc.description | This is the published version. Copyright 2014 American Institute of Physics | en_US |
dc.description.abstract | Efficient and noninvasive generation of cavitation bubbles in soft tissue is a challenging task due to the lack of cavitation nuclei (i.e., pre-existing gas bubbles). In this study, we present a method to generate and enhance cavitation activity based on the utilization of two consecutive ultrasound waves at different frequencies. First, a high frequency (5 MHz) high intensity focused ultrasound (HIFU) wave was applied to a tissue-mimicking phantom to induce a rapid temperature rise in the ultrasound focal region. Immediately following the high frequency HIFU wave, a low frequency (1 MHz) HIFU wave was applied to the same focal region to induce acoustic cavitation. We found that cavitation activity was enhanced when the temperature in the tissue-mimicking phantom was first elevated by the high frequency HIFU wave. The enhancement was greater when a higher intensity of high frequency HIFU wave was applied. This result may be due to the temporary super-saturation of air in the initially air-saturated test samples and the reduction of surface tension at an elevated temperature. | en_US |
dc.publisher | American Institute of Physics | en_US |
dc.subject | Cavitation | en_US |
dc.subject | Bubble dynamics | en_US |
dc.subject | Acoustic cavitation | en_US |
dc.subject | Ultrasonography | en_US |
dc.subject | Sound pressure | en_US |
dc.title | Enhanced cavitation by using two consecutive ultrasound waves at different frequencies | en_US |
dc.type | Article | |
kusw.kuauthor | Yang, Xinmai | |
kusw.kuauthor | Jo, Janggun | |
kusw.kudepartment | Mechanical Engineering | en_US |
dc.identifier.doi | 10.1063/1.4902118 | |
kusw.oaversion | Scholarly/refereed, publisher version | |
kusw.oapolicy | This item meets KU Open Access policy criteria. | |
dc.rights.accessrights | openAccess | |