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Intramyocardial sustained delivery of placental growth factor using nanoparticles as a vehicle for delivery in the rat infarct model
dc.contributor.author | Binsalamah, Ziyad Mohammed | |
dc.contributor.author | Paul, Arghya | |
dc.contributor.author | Khan, Afshan Afsar | |
dc.contributor.author | Prakash, Satya | |
dc.contributor.author | Shum-Tim, Dominique | |
dc.date.accessioned | 2015-10-14T16:20:29Z | |
dc.date.available | 2015-10-14T16:20:29Z | |
dc.date.issued | 2011-10-31 | |
dc.identifier.citation | Shum-Tim, Dominique, Arghya Paul, Afshan Afsar Khan, Satya Prakash, and Dominique Shum-Tim. "Intramyocardial Sustained Delivery of Placental Growth Factor Using Nanoparticles as a Vehicle for Delivery in the Rat Infarct Model." International Journal of Nanomedicine IJN (2011): 2667. http://dx.doi.org/10.2147/IJN.S25175 | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/18690 | |
dc.description.abstract | Acute myocardial ischemia results in scar formation with ventricular dilatation and eventually heart failure. Placental growth factor (PlGF) is reported to stimulate angiogenesis and improve cardiac function. In this study, it was hypothesized that intramyocardial injection of PlGF contained in nanoparticles can be released at the site of action for an extended time period as a sustained slow-release protective mechanism that accelerates myocardial recovery in a rat model of ischemic cardiomyopathy. | en_US |
dc.publisher | Dove Medical Press | en_US |
dc.rights | This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution - Non Commercial (unported, v3.0) License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress.com/permissions.php | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/3.0/ | |
dc.subject | Nanotechnology | en_US |
dc.subject | Serum cytokines | en_US |
dc.subject | Myocardial therapy | en_US |
dc.subject | Angiogenesis | en_US |
dc.subject | Regenerative medicine | en_US |
dc.title | Intramyocardial sustained delivery of placental growth factor using nanoparticles as a vehicle for delivery in the rat infarct model | en_US |
dc.type | Article | |
kusw.kuauthor | Paul, Arghya | |
kusw.kudepartment | Chemical & Petroleum Engr | en_US |
dc.identifier.doi | 10.2147/IJN.S25175 | |
kusw.oaversion | Scholarly/refereed, publisher version | |
kusw.oapolicy | This item meets KU Open Access policy criteria. | |
dc.rights.accessrights | openAccess |
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Except where otherwise noted, this item's license is described as: This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution - Non Commercial (unported, v3.0) License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress.com/permissions.php