Chemical and Petroleum Engineering Scholarly Works
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A Review of Brittleness Index Correlations for Unconventional Tight and Ultra-Tight Reservoirs
(MDPI, 2019-07-19)Brittleness is a key parameter in the development of the unconventional shale and tight carbonate reservoirs as it plays a role in the design of the hydraulic fractures as well as the selection of the sweet-spot locations ... -
3D cell culture stimulates the secretion of in vivo like extracellular vesicles
(Nature Research, 2019-09-10)For studying cellular communications ex-vivo, a two-dimensional (2D) cell culture model is currently used as the “gold standard”. 2D culture models are also widely used in the study of RNA expression profiles from tumor ... -
Impact of Heterogeneity on the Transient Gas Flow Process in Tight Rock
(MDPI, 2019-09-17)There exits a great challenge to evaluate the flow properties of tight porous media even at the core scale. A pulse-decay experiment is routinely used to measure the petrophysical properties of tight cores including ... -
Role of ALDH1A1 and HTRA2 expression in CCL2/CCR2-mediated breast cancer cell growth and invasion
(The Company of Biologists, 2019-06-28)Chemokines mediate immune cell trafficking during tissue development, wound healing and infection. The chemokine CCL2 is best known to regulate macrophage recruitment during wound healing, infection and inflammatory diseases. ... -
Recyclable Au/SiO2-Shell/Fe3O4-Core Catalyst for the Reduction of Nitro Aromatic Compounds in Aqueous Solution
(American Chemical Society, 2019-02-22)Highly stable gold nanoparticles immobilized on the surface of amine-functionalized nanocomposite microspheres possessing a magnetite (Fe3O4) nanoparticle core and a silica (SiO2) shell (Au/SiO2-shell/Fe3O4-core) were ... -
Viscoelastic Properties of ECM-Rich Embryonic Microenvironments
(Frontiers Media, 2020-08-31)The material properties of tissues and their mechanical state is an important factor in development, disease, regenerative medicine and tissue engineering. Here we describe a microrheological measurement technique utilizing ... -
Multivalent antigen arrays exhibit high avidity binding and modulation of B cell receptor-mediated signaling to drive efficacy against experimental autoimmune encephalomyelitis
(American Chemical Society, 2017-05-05)A pressing need exists for antigen-specific immunotherapies (ASIT) that induce selective tolerance in autoimmune disease while avoiding deleterious global immunosuppression. Multivalent soluble antigen arrays (SAgAPLP:LABL), ... -
Acute B-Cell Inhibition by Soluble Antigen Arrays Is Valency-Dependent and Predicts Immunomodulation in Splenocytes
(American Chemical Society, 2019-04-17)Antigen valency plays a fundamental role in directing the nature of an immune response to be stimulatory or tolerogenic. Soluble Antigen Arrays (SAgAs) are an antigen-specific immunotherapy that combats autoimmunity through ... -
Soluble Antigen Arrays for Selective Desensitization of Insulin-Reactive B Cells
(American Chemical Society, 2019-01-25)Autoimmune diseases are believed to be highly dependent on loss of immune tolerance to self-antigens. Currently, no treatments have been successful clinically in inducing autoantigen-specific tolerance, including efforts ... -
Soluble Antigen Arrays Displaying Mimotopes Direct the Response of Diabetogenic T Cells
(American Chemical Society, 2019-06-17)Type 1 diabetes (T1D) is an autoimmune disorder which develops when insulin-producing, pancreatic beta cells are destroyed by an aberrant immune response. Current therapies for T1D either treat symptoms or cause global ... -
Microsphere-Based Osteochondral Scaffolds Carrying Opposing Gradients Of Decellularized Cartilage And Demineralized Bone Matrix
(American Chemical Society, 2016-06-23)Extracellular matrix (ECM) “raw materials” such as demineralized bone matrix (DBM) and cartilage matrix have emerged as leading scaffolding materials for osteochondral regeneration owing to their capacity to facilitate ... -
Structure-Function Relationships of the Temporomandibular Joint in Response to Altered Loading
(Quintessence Publishing, 2019-07-24)Aims: To elucidate the effects of decreased occlusal loading (DOL), with or without reloading (RL), on the structure and bite force function of the mandibular condylar fibrocartilage in skeletally mature male mice. M ... -
Estrogen signaling impacts temporomandibular joint and periodontal disease pathology
(Springer Verlag, 2020-04-30)Women experience a higher incidence of oral diseases including periodontal diseases and temporomandibular joint disease (TMD) implicating the role of estrogen signaling in disease pathology. Fluctuating levels of estrogen ... -
Impact of Engineered Carbon Nanodiamonds on the Collapse Mechanism of Model Lung Surfactant Monolayers at the Air-Water Interface
(MDPI, 2020-02-07)Understanding interactions between inhaled nanoparticles and lung surfactants (LS) present at the air-water interface in the lung, is critical to assessing the toxicity of these nanoparticles. Specifically, in this work, ... -
Conversion of CO2 in a packed–bed dielectric barrier discharge reactor
(AIP Publishing, 2018)The conversion of CO2 into CO and O2 in a quartz cylindrical packed-bed dielectric reactor has been studied using CO2 and Ar gas mixtures at atmospheric pressure and near ambient temperature with quartz wool, γ-Al2O3, and ... -
Metal-Incorporated Mesoporous Silicates: Tunable Catalytic Properties and Applications
(MDPI, 2018-01-29)A relatively new class of three-dimensional ordered mesoporous silicates, KIT-6, incorporated with Earth-abundant metals such as Zr, Nb, and W (termed as M-KIT-6), show remarkable tunability of acidity and metal dispersion ... -
Estrogen Promotes Mandibular Condylar Fibrocartilage Chondrogenesis and Inhibits Degeneration via Estrogen Receptor Alpha in Female Mice
(Nature Research, 2018-06-04)Temporomandibular joint degenerative disease (TMJ-DD) is a chronic form of TMJ disorder that specifically afflicts people over the age of 40 and targets women at a higher rate than men. Prevalence of TMJ-DD in this ... -
Review Article: Gas and vapor sorption measurements using electronic beam balances
(AIP Publishing, 2018-08-30)The beam balance is one of the oldest known measuring instruments. Until the 20th century, balances had been the most sensitive and precise instruments used for scientific measurements. The original balances used a beam ... -
Simulation and measurement of water-induced liquid-liquid phase separation of imidazolium ionic liquid mixtures
(AIP Publishing, 2018-10-29)The miscibility of ionic liquid (IL) pairs with a common cation (1-ethyl-3-methylimidazolium [C2C1im]) and different anions (bis(trifluoromethylsulfonyl)amide [TFSI], acetate [OAc], and chloride [Cl]) was investigated ...
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