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KU Med Center Dissertations and Theses: Recent submissions
Now showing items 121-140 of 464
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The effects of methyl guanidine salts on some automatic nerves of the dog
(University of Kansas, 1930) -
Neutrophil Extracellular DNA Traps as a Clinical Biomarker and Target for Improved Outcomes Following Radical Cystectomy
(University of Kansas, 2018-05-31)Title: Neutrophil Extracellular DNA Traps in Patients with Muscle-Invasive Bladder Cancer Objectives Neutrophil extracellular DNA traps (NETs) are DNA scaffolding structures released by neutrophils in response to injury, ... -
Comparison of Prediction Equations for Resting Energy Expenditure vs the KORR ReeVue Indirect Calorimeter in Obesity
(University of Kansas, 2018-05-31)An increasing number of institutions and community settings are assessing resting energy expenditure (REE) to tailor weight loss interventions. Resting energy expenditure can be assessed using an indirect calorimeter or ... -
Dietary Assessment as a Means to Modulate Inflammation in Patients with Prostate Cancer
(University of Kansas, 2018-05-31)Introduction Inflammation is associated with increased risk of prostate cancer. Diet can modulate inflammation through changes in energy and diet quality. Diet quality scores, assessed by measuring what individuals eat, ... -
Docosahexaenoic Acid and Childhood Blood Pressure
(University of Kansas, 2018-05-31)Background: Long chain polyunsaturated fatty acids (LCPUFAs) have been shown to reduce blood pressure (BP) while they are being consumed; however, there is also evidence from observational studies that exposure to more ... -
Mitochondrial haplotype affects histone modification profiles in MNX mice
(University of Kansas, 2018-05-31)Cancer is a growing problem. In the US, cancer is roughly tied with cardiac disease as the leading cause of death. Intriguingly, compared to the proportion of deaths attributable to primary tumors, roughly 90% of all cancer ... -
Let’s talk about sex: Does language constitute a barrier to women reporting and receiving treatment for dyspareunia in the Spanish speaking community?
(University of Kansas, 2018-05-31)Title: Let’s talk about sex: Does language constitute a barrier to women reporting and receiving treatment for dyspareunia in the Spanish speaking community? Purpose: To identify the prevalence of dyspareunia and sexual ... -
Validation of an abbreviated FFQ for assessing DHA and EPA intake in pregnant women.
(University of Kansas, 2018-05-31)Background: Docosahexaenoic acid (DHA) is an omega-3 fatty acid found in variable amounts in the diet and is often accompanied by another omega-3 fatty acid, eicosapentaenoic acid (EPA) when the food chosen is seafood. ... -
THE DIRECT INOTROPIC AND CHRONOTROPIC EFFECTS OF TRIMETHYLAMINE-N-OXIDE ON CARDIAC MUSCLE
(University of Kansas, 2018-05-31)Background: Cardiovascular disease is endemic among patients with chronic kidney disease (CKD). Growing evidence suggests the gut microbiome plays an obligatory role in cardiovascular pathogenesis. Trimethylamine-N-oxide ... -
Screen design for Borrelia burgdorferi lipoprotein secretion pathway components using periplasmic protein capture and suppressor mutations
(University of Kansas, 2018-05-31)Borrelia burgdorferi infection, aka Lyme disease, is one of the most prevalent vector borne illnesses in the world. With an estimated 300,000 infections per year in the United States alone, this pathogen places a large ... -
THE ROLE OF COMPLEMENT C3 AS A TRIGGER FOR HUMAN MACROPHAGE DEATH DURING INFECTION WITH FRANCISELLA TULARENSIS STRAIN SCHU S4
(University of Kansas, 2018-05-31)Francisella tularensis, a Tier 1 Select Agent, is a highly infectious Gram-negative bacterium that causes the potentially deadly disease tularemia. Macrophages are considered a primary target of F. tularensis and serve as ... -
Provision of Extended Office Hours at the Usual Source of Care and its Effect on Healthcare Utilization and Expenditures in the Population of Adults with Chronic Ambulatory Care Sensitive Conditions
(University of Kansas, 2018-05-31)Healthcare providers and policymakers are increasingly experimenting with innovations that decrease healthcare costs while maintaining or improving patient health. Enhancing timely access to primary care and maintaining ... -
Feature selection and classification for high-dimensional biological data under cross-validation framework
(University of Kansas, 2018-05-31)This research focuses on using statistical learning methods on high-dimensional biological data analysis. In our implementation of high-dimensional biological data analysis, we primarily utilize the statistical learning ... -
Autophagy in Head and Neck Cancer Associated Fibroblasts
(University of Kansas, 2018-05-31)Head and neck squamous cell carcinoma (HNSCC) is a devastating disease. Despite therapeutic advancements, little change in 5-year survival has been made for patients with HNSCC. To improve therapy, a better understanding ... -
Elevated O-GlcNAcylation Enhances Pro-Inflammatory Th17 Function by Altering the Lipid Microenvironment
(University of Kansas, 2018-05-31)Chronic inflammation is a feature of obesity and enhances the risk of atherosclerosis, cancer, diabetes, and autoimmunity. Specifically, pro-inflammatory Th17 and Th1 CD4+ effector T cells are increased in metabolic diseases. ... -
Understanding the Role of the Patient-Centered Medical Home is Building a Strong Primary Care Foundation in the U.S.
(University of Kansas, 2018-05-31)It is generally agreed that there is much room for improvement in the U.S. healthcare system. In international comparisons, health care in the U.S. is consistently the most expensive and the U.S. lags other western ... -
Essential Host Factors for Human Parvovirus B19 Replication
(University of Kansas, 2018-05-31)Parvovirus B19 (B19V) is a small, non-enveloped virus that contains a single-stranded DNA (ssDNA) genome of 5.6 kb in size. B19V is pathogenic to humans and causes bone marrow failure diseases and various other inflammatory ... -
Genetic alterations in Adult T cell leukemia
(University of Kansas, 2017-12-31)Human T-cell leukemia virus type 1 (HTLV-1), which infects more than 20 million people worldwide, is known to cause adult T-cell leukemia (ATL). Even those patients treated with intense chemotherapy have a poor prognosis ... -
A QUALITATIVE DESCRIPTIVE STUDY EXPLORING ASSOCIATE DEGREE NURSING FACULTY’S EXPERIENCES TEACHING ELECTRONIC HEALTH RECORD SYSTEMS USE
(University of Kansas, 2017-12-31)There has been a persistent call for nursing education to prepare students to practice safely and competently in the technology-rich, information-laden healthcare system. The growth of the national health information ... -
Roles of CCN5 in regulating progression and therapeutic sensitivity of breast cancer
(University of Kansas, 2017-12-31)Breast cancer is one of the deadliest malignancies worldwide and also in the United States. Patients with triple negative breast cancer (TNBC), where the cancer cells do not express nuclear hormone receptors and human ...