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A low-cost open-source SNP genotyping platform for association mapping applications
dc.contributor.author | Macdonald, Stuart J. | |
dc.contributor.author | Pastinen, Tomi | |
dc.contributor.author | Genissel, Anne | |
dc.contributor.author | Cornforth, Theodore W. | |
dc.contributor.author | Long, Anthony D. | |
dc.date.accessioned | 2014-08-13T17:27:13Z | |
dc.date.available | 2014-08-13T17:27:13Z | |
dc.date.issued | 2005-12-02 | |
dc.identifier.citation | Macdonald, S.J., Pastinen, T., Genissel, A., Cornforth, T.W., and Long, A.D. A low-cost open-source SNP genotyping platform for association mapping applications. Genome Biology 2005, 6:R105. http://dx.doi.org/10.1186/gb-2005-6-12-r105 | |
dc.identifier.uri | http://hdl.handle.net/1808/14915 | |
dc.description.abstract | Association mapping aimed at identifying DNA polymorphisms that contribute to variation in complex traits entails genotyping a large number of single-nucleotide polymorphisms (SNPs) in a very large panel of individuals. Few technologies, however, provide inexpensive high-throughput genotyping. Here, we present an efficient approach developed specifically for genotyping large fixed panels of diploid individuals. The cost-effective, open-source nature of our methodology may make it particularly attractive to those working in nonmodel systems. | |
dc.publisher | BioMed Central | |
dc.rights | This is and Open Access article distributed under the terms of the Creative Commons license (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |
dc.rights.uri | http://creativecommons.org/licenses/by/2.0 | |
dc.title | A low-cost open-source SNP genotyping platform for association mapping applications | |
dc.type | Article | |
kusw.kuauthor | Macdonald, Stuart J. | |
kusw.kudepartment | Molecular Biosciences | |
kusw.oastatus | na | |
dc.identifier.doi | 10.1186/gb-2005-6-12-r105 | |
kusw.oaversion | Scholarly/refereed, publisher version | |
kusw.oapolicy | This item does not meet KU Open Access policy criteria. | |
dc.rights.accessrights | openAccess |
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Except where otherwise noted, this item's license is described as: This is and Open Access article distributed under the terms of the Creative Commons license (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.