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Construct validity of a continuous metabolic syndrome score in children
dc.contributor.author | Eisenmann, Joey C. | |
dc.contributor.author | Laurson, Kelly R. | |
dc.contributor.author | DuBose, Katrina D. | |
dc.contributor.author | Smith, Bryan K. | |
dc.contributor.author | Donnelly, Joseph E. | |
dc.date.accessioned | 2014-01-17T20:16:53Z | |
dc.date.available | 2014-01-17T20:16:53Z | |
dc.date.issued | 2010-01-28 | |
dc.identifier.citation | Eisenmann, Joey C, Kelly R Laurson, Katrina D DuBose, Bryan K Smith, and Joseph E Donnelly. 2010. “Construct Validity of a Continuous Metabolic Syndrome Score in Children.” Diabetology & Metabolic Syndrome 2:8. http://dx.doi.org/10.1186/1758-5996-2-8. | |
dc.identifier.uri | http://hdl.handle.net/1808/12811 | |
dc.description.abstract | Objective: The primary purpose of this study was to examine the construct validity of a continuous metabolic syndrome score (cMetS) in children. The secondary purpose was to identify a cutpoint value(s) for an adverse cMetS based on receiver operating characteristic (ROC) curve analysis. Methods: 378 children aged 7 to 9 years were assessed for the metabolic syndrome which was determined by age-modified cutpoints. High-density-lipoprotein cholesterol, triglycerides, the homeostasis assessment model of insulin resistance, mean arterial pressure, and waist circumference were used to create a cMetS for each subject. Results: About half of the subjects did not possess any risk factors while about 5% possessed the metabolic syndrome. There was a graded relationship between the cMetS and the number of adverse risk factors. The cMetS was lowest in the group with no adverse risk factors (-1.59 ± 1.76) and highest in those possessing the metabolic syndrome (≥3 risk factors) (7.05 ± 2.73). The cutoff level yielding the maximal sensitivity and specificity for predicting the presence of the metabolic syndrome was a cMetS of 3.72 (sensitivity = 100%, specificity = 93.9%, and the area of the curve = 0.978 (0.957-0.990, 95% confidence intervals). Conclusion: The results demonstrate the construct validity for the cMetS in children. Since there are several drawbacks to identifying a single cut-point value for the cMetS based on this sample, we urge researchers to use the approach herein to validate and create a cMetS that is specific to their study population. | |
dc.publisher | BioMed Central | |
dc.rights | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |
dc.rights.uri | http://creativecommons.org/licenses/by/2.0 | |
dc.title | Construct validity of a continuous metabolic syndrome score in children | |
dc.type | Article | |
kusw.kuauthor | Smith, Bryan K. | |
kusw.kuauthor | Donnelly, Joseph E. | |
kusw.kudepartment | Applied Behavioral Science | |
kusw.kudepartment | Bureau of Child Research | |
kusw.oastatus | fullparticipation | |
dc.identifier.doi | 10.1186/1758-5996-2-8 | |
kusw.oaversion | Scholarly/refereed, publisher version | |
kusw.oapolicy | This item meets KU Open Access policy criteria. | |
dc.rights.accessrights | openAccess |
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Except where otherwise noted, this item's license is described as: This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.