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Revisiting the Plasmodium falciparum RIFIN family: from comparative genomics to 3D-model prediction.

dc.contributor.authorBultrini, Emanuele
dc.contributor.authorMukherjee, Srayanta
dc.contributor.authorZhang, Yang
dc.contributor.authorSilvestrini, Francesco
dc.contributor.authorAlano, Pietro
dc.contributor.authorPizzi, Elisabetta
dc.date.accessioned2014-01-17T18:19:29Z
dc.date.available2014-01-17T18:19:29Z
dc.date.issued2009-09-21
dc.identifier.citationBultrini, Emanuele, Kevin Brick, Srayanta Mukherjee, Yang Zhang, Francesco Silvestrini, Pietro Alano, and Elisabetta Pizzi. 2009. “Revisiting the Plasmodium Falciparum RIFIN Family: From Comparative Genomics to 3D-Model Prediction.” BMC Genomics 10: 445. http://dx.doi.org/10.1186/1471-2164-10-445
dc.identifier.urihttp://hdl.handle.net/1808/12764
dc.description.abstractSubtelomeric RIFIN genes constitute the most abundant multigene family in Plasmodium falciparum. RIFIN products are targets for the human immune response and contribute to the antigenic variability of the parasite. They are transmembrane proteins grouped into two subfamilies (RIF_A and RIF_B). Although recent data show that RIF_A and RIF_B have different subcellular localisations and possibly different functions, the same structural organisation has been proposed for members of the two sub-families. Despite recent advances, our knowledge of the regulation of RIFIN gene expression is still poor and the biological role of the protein products remain obscure.
dc.language.isoen_US
dc.publisherBioMed Central
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.rights.urihttp://creativecommons.org/licenses/by/2.0
dc.titleRevisiting the Plasmodium falciparum RIFIN family: from comparative genomics to 3D-model prediction.
dc.typeArticle
kusw.kuauthorMukherjee, Srayanta
kusw.kuauthorZhang, Yang
kusw.kudepartmentDepartment of Molecular Biosciences
kusw.oastatusfullparticipation
dc.identifier.doi10.1186/1471-2164-10-445
kusw.oaversionScholarly/refereed, publisher version
kusw.oapolicyThis item meets KU Open Access policy criteria.
dc.rights.accessrightsopenAccess


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This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Except where otherwise noted, this item's license is described as: This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.