ATTENTION: The software behind KU ScholarWorks is being upgraded to a new version. Starting July 15th, users will not be able to log in to the system, add items, nor make any changes until the new version is in place at the end of July. Searching for articles and opening files will continue to work while the system is being updated.
If you have any questions, please contact Marianne Reed at mreed@ku.edu .
KU ScholarWorks: Recent submissions
Now showing items 1641-1660 of 29499
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A 3D–Predicted Structure of the Amine Oxidase Domain of Lysyl Oxidase–Like 2
(MDPI, 2022-11-02)Lysyl oxidase–like 2 (LOXL2) has been recognized as an attractive drug target for anti–fibrotic and anti–tumor therapies. However, the structure–based drug design of LOXL2 has been very challenging due to the lack of ... -
Size of the protein-protein energy funnel in crowded environment
(Frontiers Media, 2022-11-08)Association of proteins to a significant extent is determined by their geometric complementarity. Large-scale recognition factors, which directly relate to the funnel-like intermolecular energy landscape, provide important ... -
Peptide Carbocycles: From −SS– to −CC– via a Late-Stage “Snip-and-Stitch”
(American Chemical Society, 2022-10-28)One way to improve the therapeutic potential of peptides is through cyclization. This is commonly done using a disulfide bond between two cysteine residues in the peptide. However, disulfide bonds are susceptible to reductive ... -
Diversity in Monographs: Selectors, Acquisitions, Publishers, and Vendors
(2023-01-02)In 2020 the University of Kansas Libraries began a year-long diversity audit of the circulating monograph collection. The study, which utilized the checklist method evaluated the Libraries’ holdings based on a curated list ... -
Understanding the social and community support experiences of sexual and gender minority individuals in 12-Step programs
(Taylor and Francis Group, 2023-01-25)Sexual and gender minority individuals (e.g., gay, bisexual, non-binary, transgender; SGMI) are 2-6 times as likely as cisgender heterosexual individuals to experience alcohol or other substance use disorders. SGMI participate ... -
Insight into the Spatial Arrangement of the Lysine Tyrosylquinone and Cu2+ in the Active Site of Lysyl Oxidase-like 2
(MDPI, 2022-11-12)Lysyl oxidase-2 (LOXL2) is a Cu2+ and lysine tyrosylquinone (LTQ)-dependent amine oxidase that catalyzes the oxidative deamination of peptidyl lysine and hydroxylysine residues to promote crosslinking of extracellular ... -
A web-based interface to calculate phonological neighborhood density for words and nonwords in Modern Standard Arabic
(Springer, 2022-01-10)The availability of online databases (e.g., Balota et al., 2007) and calculators (e.g., Storkel & Hoover, 2010) has contributed to an increase in psycholinguistic-related research, to the development of evidence-based ... -
Novel hydrogel system eliminates subculturing and improves retention of nonsenescent mesenchymal stem cell populations
(Future Science Group, 2022-10-12)Aim: To compare the physiological behavior of mesenchymal stem/stromal cells (MSCs) within an expandable tissue-mimetic 3D system relative to in vitro expansion in a traditional 2D system. Methods: Adipose-derived MSCs ... -
Supporting the inclusion and retention of autistic students: Exploring teachers' and paraeducators' use of evidence-based practices in public elementary schools
(Frontiers Media, 2022-12-06)Introduction: Educators in public schools are required to serve students in their least restrictive environment. While many evidence-based practices (EBPs), defined as practices and strategies shown by research to have ... -
Using Actigraphy to Assess Chronotype and Physical Activity in Older Adults
(Oxford University Press, 2022-12-20)Chronotype refers to the time of day that people prefer to be active or to sleep and varies predictably across the lifespan. In younger samples, the morning-chronotype is related to greater levels of physical activity (PA) ... -
Context-Dependent Sexual Changes During Women's Midlife Transitions
(Oxford University Press, 2022-12-20)For women, midlife represents an important stage of transition, including shifts in physiological, social, and sexual experiences. Prior research demonstrates that women’s sexuality is more dynamic and context-dependent ... -
Member Checking Gerontology: The Case of Retirement
(Oxford University Press, 2022-12-20)Gerontology has long been a public-facing field with an applied focus. As such, the credibility of gerontology’s conclusions and guidance about aging are crucial, our advice having relevance and impact in proportion to its ... -
Improvements of Existing Knowledge Management Practices in the Consumer Electronics Industry
(2022-12-16)This Field Project report investigated best practices for Knowledge Management (KM) and Knowledge Management Systems (KMSs) and sought to devise a recommended action plan for the author's employer's existing KMS. A literature ... -
Cognitive networks detect structural patterns and emotional complexity in suicide notes
(Frontiers Media, 2022-12-08)Communicating one's mindset means transmitting complex relationships between concepts and emotions. Using network science and word co-occurrences, we reconstruct conceptual associations as communicated in 139 genuine suicide ... -
Colour scales with climate in North American ratsnakes: a test of the thermal melanism hypothesis using community science images
(The Royal Society, 2022-12-21)Animal colour is a complex trait shaped by multiple selection pressures that can vary across geography. The thermal melanism hypothesis predicts that darker coloration is beneficial to animals in colder regions because it ... -
Combination Treatment of Withalongolide a Triacetate with Cisplatin Induces Apoptosis by Targeting Translational Initiation, Migration, and Epithelial to Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma
(MDPI, 2022-12-19)Treatment regimens for head and neck squamous cell carcinoma (HNSCC) typically include cisplatin and radiotherapy and are limited by toxicities. We have identified naturally derived withalongolide A triacetate (WGA-TA) ... -
The genomic scale of fluctuating selection in a natural plant population
(Oxford University Press, 2022-12-11)This study characterizes evolution at ≈1.86 million Single Nucleotide Polymorphisms (SNPs) within a natural population of yellow monkeyflower (Mimulus guttatus). Most SNPs exhibit minimal change over a span of 23 generations ... -
Convergent evolution of elaborate nests as structural defences in birds
(The Royal Society, 2022-12-21)The pendent nests of some weaverbird and icterid species are among the most complex structures built by any animal, but why they have evolved remains to be explained. The precarious attachments and extended entrance tunnels ... -
Racial/ethnic differences in the relationship between wealth and health across young adulthood
(Elsevier, 2023-03-21)Background Although the relationship between socioeconomic position (SEP) and health has been well documented, very few prior investigations have examined the time-varying association between wealth and health across ... -
Discovery of malathion resistance QTL in Drosophila melanogaster using a bulked phenotyping approach
(Oxford University Press, 2022-10-17)Drosophila melanogaster has proved an effective system with which to understand the evolutionary genetics and molecular mechanisms of insecticide resistance. Insecticide use has left signatures of selection in the fly ...