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Similarity searches in genome-wide numerical data sets

dc.contributor.authorGalina Glazkoen_US
dc.contributor.authorMichael Colemanen_US
dc.contributor.authorArcady Mushegianen_US
dc.date.accessioned2009-05-05T16:15:57Z
dc.date.available2009-05-05T16:15:57Z
dc.date.issued2008-07-25en_US
dc.identifier.citationGalina Glazko;Michael Coleman;Arcady Mushegian: Similarity searches in genome-wide numerical data sets. Biology Direct 2006, 1(1):13.en_US
dc.identifier.urihttp://hdl.handle.net/2271/615en_US
dc.description.abstractWe present psi-square, a program for searching the space of gene vectors. The program starts with a gene vector, i.e., the set of measurements associated with a gene, and finds similar vectors, derives a probabilistic model of these vectors, then repeats search using this model as a query, and continues to update the model and search again, until convergence. When applied to three different pathway-discovery problems, psi-square was generally more sensitive and sometimes more specific than the ad hoc methods developed for solving each of these problems before.REVIEWERS:This article was reviewed by King Jordan, Mikhail Gelfand, Nicolas Galtier and Sarah Teichmann.en_US
dc.languageenen_US
dc.language.isoen_USen_US
dc.publisherBioMedCentralen_US
dc.relation.isversionofhttp://www.biology-direct.com/content/1/1/13en_US
dc.relation.hasversionhttp://www.biomedcentral.com/content/pdf/1745-6150-1-13.pdfen_US
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en_US
dc.rights.urihttp://creativecommons.org/licenses/by/2.0en_US
dc.titleSimilarity searches in genome-wide numerical data setsen_US
dc.typeArticleen_US
dc.identifier.doi10.1186/1745-6150-1-13en_US
dc.identifier.pmidPMC18655715en_US
dc.rights.accessrightsopenAccessen_US
dc.date.captured2009-04-27en_US


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This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Except where otherwise noted, this item's license is described as: This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.