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One-Pot Synthesis of (E)-2-(3-Oxoindolin-2-ylidene)-2-arylacetonitriles

dc.contributor.authorAksenov, Nicolai A.
dc.contributor.authorAksenov, Alexander V.
dc.contributor.authorKurenkov, Igor A.
dc.contributor.authorKirillov, Nikita K.
dc.contributor.authorAksenov, Dmitrii A.
dc.contributor.authorArutiunov, Nikolai A.
dc.contributor.authorAksenova, Daria S.
dc.contributor.authorRubin, Michael
dc.date.accessioned2022-07-11T18:43:27Z
dc.date.available2022-07-11T18:43:27Z
dc.date.issued2022-04-28
dc.identifier.citationAksenov, N.A.; Aksenov, A.V.; Kurenkov, I.A.; Kirillov, N.K.; Aksenov, D.A.; Arutiunov, N.A.; Aksenova, D.S.; Rubin, M. One-Pot Synthesis of (E)-2-(3-Oxoindolin-2-ylidene)-2-arylacetonitriles. Molecules 2022, 27, 2808. https://doi.org/10.3390/molecules27092808en_US
dc.identifier.urihttp://hdl.handle.net/1808/32819
dc.description.abstractA highly efficient and expeditious one-pot approach towards 2-(3-oxoindolin-2-yl)acetonitriles was designed, which involves a base-assisted aldol reaction of ortho-nitroacetophenones, followed by hydrocyanation, triggering an unusual reductive cyclization reaction.en_US
dc.publisherMDPIen_US
dc.rights© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.en_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.subjectNitroalkanesen_US
dc.subjectBrønsted acid catalysisen_US
dc.subjectIndolesen_US
dc.subjectRearrangementsen_US
dc.subjectCascade transformationsen_US
dc.titleOne-Pot Synthesis of (E)-2-(3-Oxoindolin-2-ylidene)-2-arylacetonitrilesen_US
dc.typeArticleen_US
kusw.kuauthorRubin, Michael
kusw.kudepartmentChemistryen_US
dc.identifier.doi10.3390/molecules27092808en_US
dc.identifier.orcidhttps://orcid.org/ 0000-0002-7125-9066en_US
dc.identifier.orcidhttps://orcid.org/ 0000-0002-0911-4093en_US
dc.identifier.orcidhttps://orcid.org/ 0000-0002-1668-9311en_US
kusw.oaversionScholarly/refereed, publisher versionen_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.identifier.pmidPMC35566159en_US
dc.rights.accessrightsopenAccessen_US


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© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
Except where otherwise noted, this item's license is described as: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.