ATTENTION: The software behind KU ScholarWorks is being upgraded to a new version. Starting July 15th, users will not be able to log in to the system, add items, nor make any changes until the new version is in place at the end of July. Searching for articles and opening files will continue to work while the system is being updated.
If you have any questions, please contact Marianne Reed at mreed@ku.edu .
The Functions of the Mammalian Methionine Sulfoxide Reductase System and Related Diseases
dc.contributor.author | Jiang, Beichen | |
dc.contributor.author | Moskovitz, Jackob | |
dc.date.accessioned | 2020-12-02T15:45:45Z | |
dc.date.available | 2020-12-02T15:45:45Z | |
dc.date.issued | 2018-09-18 | |
dc.identifier.citation | Jiang, B., & Moskovitz, J. (2018). The Functions of the Mammalian Methionine Sulfoxide Reductase System and Related Diseases. Antioxidants (Basel, Switzerland), 7(9), 122. https://doi.org/10.3390/antiox7090122 | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/30953 | |
dc.description | This work is licensed under a Creative Commons Attribution 4.0 International License. | en_US |
dc.description.abstract | This review article describes and discusses the current knowledge on the general role of the methionine sulfoxide reductase (MSR) system and the particular role of MSR type A (MSRA) in mammals. A powerful tool to investigate the contribution of MSRA to molecular processes within a mammalian system/organism is the MSRA knockout. The deficiency of MSRA in this mouse model provides hints and evidence for this enzyme function in health and disease. Accordingly, the potential involvement of MSRA in the processes leading to neurodegenerative diseases, neurological disorders, cystic fibrosis, cancer, and hearing loss will be deliberated and evaluated. | en_US |
dc.description.sponsorship | Hedwig Miller Fund for Aging Research | en_US |
dc.publisher | MDPI | en_US |
dc.rights | © 2018 by the authors. Licensee MDPI, Basel, Switzerland. | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | en_US |
dc.subject | Methionine sulfoxide reductase | en_US |
dc.subject | Methionine oxidation | en_US |
dc.subject | Oxidative stress | en_US |
dc.title | The Functions of the Mammalian Methionine Sulfoxide Reductase System and Related Diseases | en_US |
dc.type | Article | en_US |
kusw.kuauthor | Jiang, Beichen | |
kusw.kuauthor | Moskovitz, Jackob | |
kusw.kudepartment | Pharmacology and Toxicology | en_US |
dc.identifier.doi | 10.3390/antiox7090122 | en_US |
dc.identifier.orcid | https://orcid.org/0000-0001-7694-8074 | en_US |
kusw.oaversion | Scholarly/refereed, publisher version | en_US |
kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
dc.identifier.pmid | PMC6162418 | en_US |
dc.rights.accessrights | openAccess | en_US |
Files in this item
This item appears in the following Collection(s)
-
Pharmacy Scholarly Works [299]