The Functions of the Mammalian Methionine Sulfoxide Reductase System and Related Diseases
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Issue Date
2018-09-18Author
Jiang, Beichen
Moskovitz, Jackob
Publisher
MDPI
Type
Article
Article Version
Scholarly/refereed, publisher version
Rights
© 2018 by the authors. Licensee MDPI, Basel, Switzerland.
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Show full item recordAbstract
This review article describes and discusses the current knowledge on the general role of the methionine sulfoxide reductase (MSR) system and the particular role of MSR type A (MSRA) in mammals. A powerful tool to investigate the contribution of MSRA to molecular processes within a mammalian system/organism is the MSRA knockout. The deficiency of MSRA in this mouse model provides hints and evidence for this enzyme function in health and disease. Accordingly, the potential involvement of MSRA in the processes leading to neurodegenerative diseases, neurological disorders, cystic fibrosis, cancer, and hearing loss will be deliberated and evaluated.
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This work is licensed under a Creative Commons Attribution 4.0 International License.
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- Pharmacy Scholarly Works [293]
Citation
Jiang, B., & Moskovitz, J. (2018). The Functions of the Mammalian Methionine Sulfoxide Reductase System and Related Diseases. Antioxidants (Basel, Switzerland), 7(9), 122. https://doi.org/10.3390/antiox7090122
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