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dc.contributor.authorMotiwala, Hashim F.
dc.contributor.authorYin, Qin
dc.contributor.authorAubé, Jeffrey
dc.identifier.citationMotiwala, H. F., Yin, Q., & Aubé, J. (2015). Improved Schmidt Conversion of Aldehydes to Nitriles Using Azidotrimethylsilane in 1,1,1,3,3,3-Hexafluoro-2-propanol. Molecules (Basel, Switzerland), 21(1), E45.
dc.descriptionThis work is licensed under a Creative Commons Attribution 4.0 International License.en_US
dc.description.abstractThe Schmidt reaction of aromatic aldehydes using a substoichiometric amount (40 mol %) of triflic acid is described. Low catalyst loading was enabled by a strong hydrogen-bond-donating solvent hexafluoro-2-propanol (HFIP). This improved protocol tolerates a broad scope of aldehydes with diverse functional groups and the corresponding nitriles were obtained in good to high yields without the need for aqueous work up.en_US
dc.description.sponsorshipUniversity of Kansasen_US
dc.rights© 2015 by the authors. Licensee MDPI, Basel, Switzerland.en_US
dc.subjectSchmidt reactionen_US
dc.titleImproved Schmidt Conversion of Aldehydes to Nitriles Using Azidotrimethylsilane in 1,1,1,3,3,3-Hexafluoro-2-propanolen_US
kusw.kuauthorMotiwala, Hashim F.
kusw.kuauthorYin, Qin
kusw.kuauthorAubé, Jeffrey
kusw.kudepartmentMedicinal Chemistryen_US
kusw.oanotesPer Sherpa Romeo 12/01/2020:

Molecules [Open panel below]Publication Information TitleMolecules [English] ISSNsElectronic: 1420-3049 URL PublishersMDPI [Commercial Publisher] DOAJ Listing Requires APCYes [Data provided by DOAJ] [Open panel below]Publisher Policy Open Access pathways permitted by this journal's policy are listed below by article version. Click on a pathway for a more detailed view.

Published Version NoneCC BYPMC Any Repository, Journal Website, +1 OA PublishingThis pathway includes Open Access publishing EmbargoNo Embargo LicenceCC BY 4.0 Copyright OwnerAuthors Publisher DepositPubMed Central Location Any Repository Named Repository (PubMed Central) Journal Website ConditionsPublished source must be acknowledged with citation NotesAuthors are encouraged to submit their published articles to institutional repositories
kusw.oaversionScholarly/refereed, publisher versionen_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US

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© 2015 by the authors. Licensee MDPI, Basel, Switzerland.
Except where otherwise noted, this item's license is described as: © 2015 by the authors. Licensee MDPI, Basel, Switzerland.