dc.contributor.author | Kobelev, Aleksandr I. | |
dc.contributor.author | Tretyakov, Nikita A. | |
dc.contributor.author | Stepanova, Ekaterina E. | |
dc.contributor.author | Dmitriev, Maksim V. | |
dc.contributor.author | Rubin, Michael | |
dc.contributor.author | Maslivets, Andrey N. | |
dc.date.accessioned | 2020-06-12T21:17:36Z | |
dc.date.available | 2020-06-12T21:17:36Z | |
dc.date.issued | 2019-11-27 | |
dc.identifier.citation | Kobelev, A. I., Tretyakov, N. A., Stepanova, E. E., Dmitriev, M. V., Rubin, M., & Maslivets, A. N. (2019). Facile regiodivergent synthesis of spiro pyrrole-substituted pseudothiohydantoins and thiohydantoins via reaction of [e]-fused 1H-pyrrole-2,3-diones with thiourea. Beilstein journal of organic chemistry, 15, 2864–2871. https://doi.org/10.3762/bjoc.15.280 | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/30468 | |
dc.description | This work is licensed under a Creative Commons Attribution 4.0 International License. | en_US |
dc.description.abstract | A highly divergent synthesis of regioisomeric thiohydantoins and pseudothiohydantoins spiro-fused to a pharmacologically valuable pyrrole-2-one fragment involving the reaction of [e]-fused 1H-pyrrole-2,3-diones with thioureas was developed. The obtained spiro pseudothiohydantoin derivatives were found to undergo a pseudothiohydantoin–thiohydantoin rearrangement. The reactions were shown to proceed under catalyst-free conditions in good yields, and the products were isolated without applying preparative chromatography methods. | en_US |
dc.publisher | Beilstein-Institut | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | en_US |
dc.subject | Diversity-oriented synthesis | en_US |
dc.subject | Hydantoin | en_US |
dc.subject | Nitrogen heterocycles | en_US |
dc.subject | Rearrangement | en_US |
dc.subject | Thiourea | en_US |
dc.title | Facile regiodivergent synthesis of spiro pyrrole-substituted pseudothiohydantoins and thiohydantoins via reaction of [e]-fused 1H-pyrrole-2,3-diones with thiourea | en_US |
dc.type | Article | en_US |
kusw.kuauthor | Rubin, Michael | |
kusw.kudepartment | Chemistry | en_US |
dc.identifier.doi | 10.3762/bjoc.15.280 | en_US |
dc.identifier.orcid | https://orcid.org/0000-0001-8606-7908 | en_US |
dc.identifier.orcid | https://orcid.org/0000-0002-6375-9407 | en_US |
dc.identifier.orcid | https://orcid.org/0000-0002-5851-3082 | en_US |
dc.identifier.orcid | https://orcid.org/0000-0002-8817-0543 | en_US |
dc.identifier.orcid | https://orcid.org/0000-0002-1668-9311 | en_US |
dc.identifier.orcid | https://orcid.org/0000-0001-7148-4450 | en_US |
kusw.oaversion | Scholarly/refereed, publisher version | en_US |
kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
dc.identifier.pmid | PMC6902856 | en_US |
dc.rights.accessrights | openAccess | en_US |