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Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

dc.contributor.authorMasson, Glenn R.
dc.contributor.authorBurke, John E.
dc.contributor.authorAhn, Natalie G.
dc.contributor.authorAnand, Ganesh S.
dc.contributor.authorBorchers, Christoph
dc.contributor.authorBrier, Sébastien
dc.contributor.authorBou-Assaf, George M.
dc.contributor.authorEngen, John R.
dc.contributor.authorEnglander, S. Walter
dc.contributor.authorFaber, Johan
dc.contributor.authorGarlish, Rachel
dc.contributor.authorGriffin, Patrick R.
dc.contributor.authorGross, Michael L.
dc.contributor.authorGuttman, Miklos
dc.contributor.authorHamuro, Yoshitomo
dc.contributor.authorHeck, Albert J. R.
dc.contributor.authorHoude, Damian
dc.contributor.authorIacob, Roxana E.
dc.contributor.authorJørgensen, Thomas J. D.
dc.contributor.authorKaltashov, Igor A.
dc.contributor.authorKlinman, Judith P.
dc.contributor.authorKonermann, Lars
dc.contributor.authorMan, Petr
dc.contributor.authorMayne, Leland
dc.contributor.authorPascal, Bruce D.
dc.contributor.authorReichmann, Dana
dc.contributor.authorSkehel, Mark
dc.contributor.authorSnijder, Joost
dc.contributor.authorStrutzenberg, Timothy S.
dc.contributor.authorUnderbakke, Eric S.
dc.contributor.authorWagner, Cornelia
dc.contributor.authorWales, Thomas E.
dc.contributor.authorWalters, Benjamin T.
dc.contributor.authorWeis, David D.
dc.contributor.authorWilson, Derek J.
dc.contributor.authorWintrode, Patrick L.
dc.contributor.authorZhang, Zhongqi
dc.contributor.authorZheng, Jie
dc.contributor.authorSchriemer, David C.
dc.contributor.authorRand, Kasper D.
dc.date.accessioned2019-11-07T22:06:51Z
dc.date.available2019-11-07T22:06:51Z
dc.date.issued2019-06-27
dc.identifier.citationMasson, G. R., Burke, J. E., Ahn, N. G., Anand, G. S., Borchers, C., Brier, S., … Rand, K. D. (2019). Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments. Nature methods, 16(7), 595–602. doi:10.1038/s41592-019-0459-yen_US
dc.identifier.urihttp://hdl.handle.net/1808/29728
dc.description.abstractHydrogen deuterium exchange mass spectrometry (HDX-MS) is a powerful biophysical technique being increasingly applied to a wide variety of problems. As the HDX-MS community continues to grow, adoption of best practices in data collection, analysis, presentation and interpretation will greatly enhance the accessibility of this technique to nonspecialists. Here we provide recommendations arising from community discussions emerging out of the first International Conference on Hydrogen-Exchange Mass Spectrometry (IC-HDX; 2017). It is meant to represent both a consensus viewpoint and an opportunity to stimulate further additions and refinements as the field advances.en_US
dc.publisherNature Researchen_US
dc.rights© The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.en_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/.en_US
dc.titleRecommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experimentsen_US
dc.typeArticleen_US
kusw.kuauthorWeis, David D.
kusw.kudepartmentPharmaceutical Chemistryen_US
dc.identifier.doi10.1038/s41592-019-0459-yen_US
dc.identifier.orcidhttps://orcid.org/0000-0002-1386-4719en_US
dc.identifier.orcidhttps://orcid.org/0000-0001-7904-9859en_US
dc.identifier.orcidhttps://orcid.org/0000-0002-6918-9476en_US
dc.identifier.orcidhttps://orcid.org/0000-0003-1159-4636en_US
dc.identifier.orcidhttps://orcid.org/0000-0002-2405-4404en_US
dc.identifier.orcidhttps://orcid.org/0000-0001-6106-4698en_US
dc.identifier.orcidhttps://orcid.org/0000-0001-5734-2843en_US
dc.identifier.orcidhttps://orcid.org/0000-0003-0315-5334en_US
dc.identifier.orcidhttps://orcid.org/0000-0003-0598-534Xen_US
dc.identifier.orcidhttps://orcid.org/0000-0003-4269-7339en_US
dc.identifier.orcidhttps://orcid.org/0000-0003-3032-1211en_US
dc.identifier.orcidhttps://orcid.org/0000-0002-7012-6085en_US
dc.identifier.orcidhttps://orcid.org/0000-0002-5202-1618en_US
dc.identifier.orcidhttps://orcid.org/0000-0002-6337-5489en_US
kusw.oaversionScholarly/refereed, author accepted manuscripten_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.identifier.pmidPMC6614034en_US
dc.rights.accessrightsOpenAccessen_US


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© The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Except where otherwise noted, this item's license is described as: © The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.