Stem cell secretome-rich nanoclay hydrogel: a dual action therapy for cardiovascular regeneration†

Waters, Renae; Pacelli, Settimio; Maloney, Ryan; Medhi, Indrani; Ahmed, Rafeeq P. H.; Paul, Arghya

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Issue Date

2016-03-31

Author

Waters, Renae

Pacelli, Settimio

Maloney, Ryan

Medhi, Indrani

Ahmed, Rafeeq P. H.

Paul, Arghya

Publisher

Royal Society of Chemistry

Type

Article

Article Version

Scholarly/refereed, author accepted manuscript

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Abstract

A nanocomposite hydrogel with photocrosslinkable micro-porous networks and a nanoclay component was successfully prepared to control the release of growth factor-rich stem cell secretome. The proven pro-angiogenic and cardioprotective potential of this new bioactive system provides a valuable therapeutic platform for cardiac tissue repair and regeneration.

Citation

Waters, R., Pacelli, S., Maloney, R., Medhi, I., Ahmed, R. P. H., & Paul, A. (2016). Stem cell secretome-rich nanoclay hydrogel: a dual action therapy for cardiovascular regeneration. Nanoscale, 8(14), 7371–7376. http://doi.org/10.1039/c5nr07806g

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