Instrumented balance and walking assessments in persons with multiple sclerosis show strong test-retest reliability
dc.contributor.author | Craig, Jordan John-William | |
dc.contributor.author | Bruetsch, Adam P. | |
dc.contributor.author | Lynch, Sharon G. | |
dc.contributor.author | Horak, Fay B. | |
dc.contributor.author | Huisinga, Jessie M. | |
dc.date.accessioned | 2017-06-07T16:01:31Z | |
dc.date.available | 2017-06-07T16:01:31Z | |
dc.date.issued | 2017-05-22 | |
dc.identifier.citation | Craig, J. J., Bruetsch, A. P., Lynch, S. G., Horak, F. B., & Huisinga, J. M. (2017). Instrumented balance and walking assessments in persons with multiple sclerosis show strong test-retest reliability. Journal of NeuroEngineering and Rehabilitation, 14, 43. http://doi.org/10.1186/s12984-017-0251-0 | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/24402 | |
dc.description | A grant from the One-University Open Access Fund at the University of Kansas was used to defray the author's publication fees in this Open Access journal. The Open Access Fund, administered by librarians from the KU, KU Law, and KUMC libraries, is made possible by contributions from the offices of KU Provost, KU Vice Chancellor for Research & Graduate Studies, and KUMC Vice Chancellor for Research. For more information about the Open Access Fund, please see http://library.kumc.edu/authors-fund.xml. | |
dc.description.abstract | BACKGROUND: There is a need for objective movement assessment for clinical research trials aimed at improving gait and balance in persons with multiple sclerosis (PwMS). Wireless inertial sensors can accurately measure numerous walking and balance parameters but these measures require evaluation of reliability in PwMS. The current study determined the test-retest reliability of wireless inertial sensor measures obtained during an instrumented standing balance test and an instrumented Timed Up and Go test in PwMS. METHODS: Fifteen PwMS and 15 healthy control subjects (HC) performed an instrumented standing balance and instrumented Timed Up and Go (TUG) test on two separate days. Ten instrumented standing balance measures and 18 instrumented TUG measures were computed from the wireless sensor data. Intraclass correlation coefficients (ICC) were calculated to determine test-retest reliability of all instrumented standing balance and instrumented TUG measures. Correlations were evaluated between the instrumented standing balance and instrumented TUG measures and self-reported walking and balance performance, fall history, and clinical disability. RESULTS: For both groups, ICCs for instrumented standing balance measures were best for spatio-temporal measures, while frequency measures were less reliable. All instrumented TUG measures exhibited good to excellent (ICCs > 0.60) test-retest reliability in PwMS and in HC. There were no correlations between self-report walking and balance scores and instrumented TUG or instrumented standing balance metrics, but there were correlations between instrumented TUG and instrumented standing balance metrics and fall history and clinical disability status. CONCLUSIONS: Measures from the instrumented standing balance and instrumented TUG tests exhibit good to excellent reliability, demonstrating their potential as objective assessments for clinical trials. A subset of the most reliable measures is recommended for measuring walking and balance in clinical settings. | en_US |
dc.publisher | BioMed Central | en_US |
dc.rights | This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | en_US |
dc.subject | Balance | en_US |
dc.subject | Walking | en_US |
dc.subject | Accelerometers | en_US |
dc.subject | Multiple sclerosis | en_US |
dc.subject | Reliability | en_US |
dc.title | Instrumented balance and walking assessments in persons with multiple sclerosis show strong test-retest reliability | en_US |
dc.type | Article | en_US |
kusw.kuauthor | Craig, Jordan J. | |
kusw.kuauthor | Huisinga, Jessie M. | |
kusw.kuauthor | Bruetsch, Adam P. | |
kusw.kuauthor | Lynch, Sharon G. | |
kusw.kudepartment | Bioengineering | en_US |
kusw.kudepartment | Landon Center on Aging | |
kusw.kudepartment | Neurology | |
dc.identifier.doi | 10.1186/s12984-017-0251-0 | en_US |
kusw.oaversion | Scholarly/refereed, publisher version | en_US |
kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
dc.identifier.pmid | PMC5441007 | en_US |
dc.rights.accessrights | openAccess |
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