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A Randomized, Controlled, Supervised, Excerise Trial in Young Overweight Men and Women: The Midwest Exercise Trial II (MET2)

dc.contributor.authorDonnelly, Joseph E.
dc.contributor.authorWashburn, Richard A.
dc.contributor.authorSmith, Bryan K.
dc.contributor.authorSullivan, Debra K.
dc.contributor.authorGibson, Cheryl A.
dc.contributor.authorHonas, Jeffery J.
dc.contributor.authorMayo, Matthew S.
dc.date.accessioned2017-06-05T18:57:57Z
dc.date.available2017-06-05T18:57:57Z
dc.date.issued2012-07
dc.identifier.citationDonnelly, J. E., Washburn, R. A., Smith, B. K., Sullivan, D. K., Gibson, C., Honas, J. J., & Mayo, M. S. (2012). A Randomized, Controlled, Supervised, Exercise Trial in Young Overweight Men and Women: The Midwest Exercise Trial II (MET2). Contemporary Clinical Trials, 33(4), 804–810. http://doi.org/10.1016/j.cct.2012.03.016en_US
dc.identifier.urihttp://hdl.handle.net/1808/24371
dc.description.abstractWe evaluated weight loss response to 16 months of supervised exercise (45 minutes/d, 5 d/wk, 75% heart-rate-reserve) in sedentary, overweight/obese participants without energy restriction in the Midwest Exercise Trial (MET1). Results indicated men lost weight, women did not. The gender differences were associated with differences in the energy expenditure of exercise (EEEx) (men = 667 ± 116; women = 439 ± 88 kcal/session) when exercise was prescribed by frequency, intensity and duration. MET2 is a randomized control trial designed and powered to examine differences in weight loss and gender in response to EEEx for men and women of 400 or 600 kcal/session, 5d/wk, for 10 months without energy restriction. One hundred forty one participants will be randomized to 1 of 2 exercise groups or a non-exercise control. EEEx will be verified by indirect calorimetry monthly during the intervention. This study will evaluate: (1) the weight change response to two levels of EEEx versus non-exercise control; (2) gender differences in weight response to two levels of EEEx; (3) potential compensatory changes in energy intake and/or daily physical activity that may explain the observed weight changes. Results from this study may impact how exercise is prescribed for weight loss and prevention of weight regain and may clarify if men and women differ in response to exercise.en_US
dc.publisherElsevieren_US
dc.rightsThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 4.0 (CC BY-NC-ND 4.0), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.en_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en_US
dc.subjectSupervised Exerciseen_US
dc.subjectEnergy Expenditureen_US
dc.subjectGenderen_US
dc.subjectWeight lossen_US
dc.subjectEnergy Balanceen_US
dc.titleA Randomized, Controlled, Supervised, Excerise Trial in Young Overweight Men and Women: The Midwest Exercise Trial II (MET2)en_US
dc.typeArticleen_US
kusw.kuauthorDonnelly, Joseph E.
kusw.kudepartmentLife Span Instituteen_US
dc.identifier.doi10.1016/j.cct.2012.03.016en_US
kusw.oaversionScholarly/refereed, author accepted manuscripten_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.identifier.pmidPMC3361612en_US
dc.rights.accessrightsopenAccess


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This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 4.0 (CC BY-NC-ND 4.0), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Except where otherwise noted, this item's license is described as: This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License 4.0 (CC BY-NC-ND 4.0), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.