dc.contributor.author | Park, Jonggu | |
dc.contributor.author | Ye, Qiang | |
dc.contributor.author | Topp, Elizabeth M. | |
dc.contributor.author | Spencer, Paulette | |
dc.date.accessioned | 2017-05-19T15:48:04Z | |
dc.date.available | 2017-05-19T15:48:04Z | |
dc.date.issued | 2009-11 | |
dc.identifier.citation | Park, J.-G., Ye, Q., Topp, E. M. and Spencer, P. (2009), Enzyme-catalyzed hydrolysis of dentin adhesives containing a new urethane-based trimethacrylate monomer. J. Biomed. Mater. Res., 91B: 562–571. doi:10.1002/jbm.b.31430 | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/24245 | |
dc.description.abstract | A new trimethacrylate monomer with urethane-linked groups, 1,1,1-tri-[4-(methacryloxyethylamino-carbonyloxy)-phenyl]ethane (MPE), was synthesized, characterized, and used as a co-monomer in dentin adhesives. Dentin adhesives containing 2-hydroxyethyl methacrylate (HEMA, 45% w/w) and 2,2-bis[4(2-hydroxy-3-methacryloyloxy-propyloxy)-phenyl] propane (BisGMA, 30% w/w) in addition to MPE (25% w/w) were formulated with H2O at 0 (MPE0), 8 (MPE8) and 16 wt % water (MPE16) to simulate the wet demineralized dentin matrix and compared with controls [HEMA/BisGMA, 45/55 w/w, at 0 (C0), 8 (C8) and 16 wt% water (C16)]. The new adhesive showed a degree of double bond conversion and mechanical properties comparable with control, with good penetration into the dentin surface and a uniform adhesive/dentin interface. On exposure to porcine liver esterase, the net cumulative methacrylic acid (MAA) release from the new adhesives was dramatically (P < 0.05) decreased relative to the control, suggesting that the new monomer improves esterase resistance. | en_US |
dc.publisher | Wiley | en_US |
dc.rights | This is the peer reviewed version of the following article: Park, J.-G., Ye, Q., Topp, E. M. and Spencer, P. (2009), Enzyme-catalyzed hydrolysis of dentin adhesives containing a new urethane-based trimethacrylate monomer. J. Biomed. Mater. Res., 91B: 562–571. doi:10.1002/jbm.b.31430. Which has been published in final form at http://doi.org/10.1002/jbm.b.31430. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving | en_US |
dc.subject | Dentin adhesives | en_US |
dc.subject | Photopolymerization | en_US |
dc.subject | Enzymatic degradation | en_US |
dc.subject | Urethane-based trimethacrylate | en_US |
dc.subject | Interface | en_US |
dc.title | Enzyme-catalyzed hydrolysis of dentin adhesive containing a new urethane-based trimethacrylate monomer | en_US |
dc.type | Article | en_US |
kusw.kuauthor | Park, Jonggu | |
kusw.kuauthor | Ye, Qiang | |
kusw.kuauthor | Topp, Elizabeth M. | |
kusw.kuauthor | Spencer, Paulette | |
kusw.kudepartment | Pharmaceutical Chemistry | en_US |
kusw.kudepartment | Mechanical Engineering | en_US |
dc.identifier.doi | 10.1002/jbm.b.31430 | en_US |
kusw.oaversion | Scholarly/refereed, author accepted manuscript | en_US |
kusw.oapolicy | This item meets KU Open Access policy criteria. | en_US |
dc.identifier.pmid | PMC2758931 | en_US |
dc.rights.accessrights | openAccess | |