Palladium-catalyzed Transformations of Salvinorin A, a Neoclerodane Diterpene from Salvia divinorum

Riley, Andrew Philip; Day, Victor W.; Navarro, Hernán A.; Prisinzano, Thomas E.

dc.contributor.author	Riley, Andrew Philip
dc.contributor.author	Day, Victor W.
dc.contributor.author	Navarro, Hernán A.
dc.contributor.author	Prisinzano, Thomas E.
dc.date.accessioned	2017-03-24T17:32:58Z
dc.date.available	2017-03-24T17:32:58Z
dc.date.issued	2013-12-06
dc.identifier.citation	Riley, A. P., Day, V. W., Navarro, H. A., & Prisinzano, T. E. (2013). Palladium-catalyzed Transformations of Salvinorin A, a Neoclerodane Diterpene from Salvia divinorum. Organic Letters, 15(23), 5936–5939. http://doi.org/10.1021/ol4027528	en_US
dc.identifier.uri	http://hdl.handle.net/1808/23484
dc.description.abstract	Transformations that selectively modify the furan ring present in a variety of naturals products would be useful in the synthesis of biological probes but remain largely underexplored. The neoclerodane diterpene salvinorin A, isolated from Salvia divinorum, is an example of a furan-containing natural product. Following selective bromination of salvinorin A, Suzuki-Miyaura and Sonogashira couplings were accomplished in moderate to good yields without hydrolyzing the labile C-2 acetate or altering the stereochemistry of the epimerizable centers.	en_US
dc.publisher	American Chemical Society	en_US
dc.rights	This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://doi.org/10.1021/ol4027528.
dc.title	Palladium-catalyzed Transformations of Salvinorin A, a Neoclerodane Diterpene from Salvia divinorum	en_US
dc.type	Article	en_US
kusw.kuauthor	Riley, Andrew P.
kusw.kuauthor	Day, Victor W.
kusw.kuauthor	Prisinzano, Thomas E.
kusw.kudepartment	Chemistry	en_US
kusw.oanotes	Per SHERPA/RoMEO 3/24/2017: uthor's Pre-print: grey tick subject to Restrictions below, author can archive pre-print (ie pre-refereeing) Restrictions: Must obtain written permission from Editor Must not violate ACS ethical Guidelines Author's Post-print: grey tick subject to Restrictions below, author can archive post-print (ie final draft post-refereeing) Restrictions: If mandated by funding agency or employer/ institution If mandated to deposit before 12 months, must obtain waiver from Institution/Funding agency or use AuthorChoice 12 months embargo Publisher's Version/PDF: cross author cannot archive publisher's version/PDF General Conditions: On author's personal website, pre-print servers, institutional website, institutional repositories or subject repositories Non-Commercial Must be accompanied by set statement (see policy) Must link to publisher version Publisher's version/PDF cannot be used	en_US
dc.identifier.doi	10.1021/ol4027528	en_US
kusw.oaversion	Scholarly/refereed, author accepted manuscript	en_US
kusw.oapolicy	This item meets KU Open Access policy criteria.	en_US
dc.rights.accessrights	openAccess

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