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dc.contributor.authorJayasinghe, Susanthi
dc.contributor.authorVenukadasula, Phanindra K. M.
dc.contributor.authorHanson, Paul R.
dc.identifier.citationJayasinghe, S., Venukadasula, P. K. M., & Hanson, P. R. (2014). An Efficient, Modular Approach for the Synthesis of (+)-Strictifolione and a Related Natural Product. Organic Letters, 16(1), 122–125.
dc.description.abstractAn efficient, library amenable, “pot economical” total synthesis of (+)-strictifolione and the related natural product, (6R)-6[(E,4R,6R)-4,6-dihydroxy-10-phenyl-1-decenyl]-5,6-dihydro-2H-2-pyrone are reported. This modular approach takes advantage of two consecutive phosphate tether-mediated, one-pot, sequential protocols, followed by a final cross metathesis to deliver both antifungal natural products in a three-pot process from the respective enantiomeric (R,R)- and (S,S)-trienes with minimal purification. A salient feature of this route is that additional protecting groups are not required as a result of the orthogonal protecting- and leaving-group properties innate to phosphate triesters.en_US
dc.publisherAmerican Chemical Societyen_US
dc.rightsThis document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see
dc.titleAn Efficient, Modular Approach for the Synthesis of (+)-Strictifolione and a Related Natural Producten_US
kusw.kuauthorJayasinghe, Susanthi
kusw.kuauthorVenukadasula, Phanindra K. M.
kusw.kuauthorHanson, Paul R.
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kusw.oaversionScholarly/refereed, author accepted manuscripten_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US

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