A Formal [4+4] Complementary Ambiphile Pairing (CAP) Reaction: A New Cyclization Pathway for ortho-Quinone Methides

Samarakoon, Thiwanka Bandara; Hur, Moon Young; Kurtz, Ryan D.; Hanson, Paul R.

dc.contributor.author	Samarakoon, Thiwanka Bandara
dc.contributor.author	Hur, Moon Young
dc.contributor.author	Kurtz, Ryan D.
dc.contributor.author	Hanson, Paul R.
dc.date.accessioned	2017-03-08T19:15:33Z
dc.date.available	2017-03-08T19:15:33Z
dc.date.issued	2010-03-21
dc.identifier.citation	Samarakoon, T. B., Hur, M. Y., Kurtz, R. D., & Hanson, P. R. (2010). A Formal [4+4] Complementary Ambiphile Pairing (CAP) Reaction: A New Cyclization Pathway for ortho-Quinone Methides. Organic Letters, 12(10), 2182–2185. http://doi.org/10.1021/ol100495w	en_US
dc.identifier.uri	http://hdl.handle.net/1808/23360
dc.description.abstract	A formal, one-pot, [4+4] cyclization pathway for the generation of 8-member sultams via in-situ generation of an ortho-quinone methide (o-QM) is reported. The pairing of ambiphilic synthons in a complementary fashion is examined whereby o-fluorobenzenesulfonamides are merged with in-situ-generated o-QM in a formal [4+4] cyclization pathway to afford 5,2,1-dibenzooxathiazocine-2,2-dioxide scaffolds under microwave (mW) conditions. The method reported represents the first use of an o-QM in a formal hetero [4+4] cyclization.	en_US
dc.publisher	American Chemical Society	en_US
dc.rights	This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/ol100495w	en_US
dc.title	A Formal [4+4] Complementary Ambiphile Pairing (CAP) Reaction: A New Cyclization Pathway for ortho-Quinone Methides	en_US
dc.type	Article	en_US
kusw.kuauthor	Samarakoon, Thiwanka B.
kusw.kuauthor	Hur, Moon y.
kusw.kuauthor	Kurtz, Ryan
kusw.kuauthor	Hanson, Paul R.
kusw.kudepartment	Chemistry	en_US
dc.identifier.doi	10.1021/ol100495w	en_US
kusw.oaversion	Scholarly/refereed, author accepted manuscript	en_US
kusw.oapolicy	This item meets KU Open Access policy criteria.	en_US
dc.rights.accessrights	openAccess

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