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    Toxicity of nanomaterials

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    forrest_toxicity.pdf (741.7Kb)
    Issue Date
    2016-01-06
    Author
    Sharifi, Shahriar
    Behzadi, Shahed
    Laurent, Sophie
    Forrest, M. Laird
    Stroeve, Pieter
    Mahmoudi, Morteza
    Publisher
    Royal Society of Chemistry
    Type
    Article
    Article Version
    Scholarly/refereed, author accepted manuscript
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    Abstract
    Nanoscience has matured significantly during the last decade as it has transitioned from bench top science to applied technology. Presently, nanomaterials are used in a wide variety of commercial products such as electronic components, sports equipment, sun creams and biomedical applications. There are few studies of the long-term consequences of nanoparticles on human health, but governmental agencies, including the United States National Institute for Occupational Safety and Health and Japan’s Ministry of Health, have recently raised the question of whether seemingly innocuous materials such as carbon-based nanotubes should be treated with the same caution afforded known carcinogens such as asbestos. Since nanomaterials are increasing a part of everyday consumer products, manufacturing processes, and medical products, it is imperative that both workers and end-users be protected from inhalation of potentially toxic NPs. It also suggests that NPs may need to be sequestered into products so that the NPs are not released into the atmosphere during the product’s life or during recycling. Further, non-inhalation routes of NP absorption, including dermal and medical injectables, must be studied in order to understand possible toxic effects. Fewer studies to date have addressed whether the body can eventually eliminate nanomaterials to prevent particle build-up in tissues or organs. This critical review discusses the biophysicochemical properties of various nanomaterials with emphasis on currently available toxicology data and methodologies for evaluating nanoparticle toxicity.
    URI
    http://hdl.handle.net/1808/23227
    DOI
    https://doi.org/10.1039/c1cs15188f
    Collections
    • Pharmaceutical Chemistry Scholarly Works [353]
    Citation
    Sharifi, Shahriar, Shahed Behzadi, Sophie Laurent, M. Laird Forrest, Pieter Stroeve, and Morteza Mahmoudi. "Toxicity of Nanomaterials." Chem. Soc. Rev. 41.6 (2012): 2323-343.

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    Contact KU ScholarWorks
    785-864-8983
    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    Image Credits
     

     

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