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dc.contributor.authorHymel, David
dc.contributor.authorCai, Sutang
dc.contributor.authorHenkhaus, Rebecca S.
dc.contributor.authorPerera, Chamani
dc.contributor.authorPeterson, Blake R.
dc.date.accessioned2017-02-22T20:46:12Z
dc.date.available2017-02-22T20:46:12Z
dc.date.issued2016-10-07
dc.identifier.citationHymel, David, Sutang Cai, Qi Sun, Rebecca S. Henkhaus, Chamani Perera, and Blake R. Peterson. "Fluorescent Mimics of Cholesterol That Rapidly Bind Surfaces of Living Mammalian Cells." Chem. Commun. 51.78 (2015): 14624-4627.en_US
dc.identifier.urihttp://hdl.handle.net/1808/23221
dc.description.abstractMammalian cells acquire cholesterol, a critical membrane constituent, through multiple mechanisms. We synthesized mimics of cholesterol, fluorescent N-alkyl-3β-cholesterylamine-glutamic acids, that are rapidly incorporated into cellular plasma membranes compared with analogous cholesteryl amides, ethers, esters, carbamates, and a sitosterol analogue. This process was inhibited by ezetimibe, indicating a receptor-mediated uptake pathway.en_US
dc.publisherRoyal Society of Chemistryen_US
dc.titleFluorescent Mimics of Cholesterol that Rapidly Bind Surfaces of Living Mammalian Cellsen_US
dc.typeArticleen_US
kusw.kuauthorPeterson, Blake R.
kusw.kudepartmentMedicinal Chemistryen_US
dc.identifier.doi10.1039/c5cc06325fen_US
kusw.oaversionScholarly/refereed, author accepted manuscripten_US
kusw.oapolicyThis item meets KU Open Access policy criteria.en_US
dc.rights.accessrightsopenAccess


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