dc.contributor.advisor | Jackson, Timothy A | |
dc.contributor.author | Leto, Domenick F. | |
dc.date.accessioned | 2017-01-08T19:51:12Z | |
dc.date.available | 2017-01-08T19:51:12Z | |
dc.date.issued | 2014-08-31 | |
dc.date.submitted | 2014 | |
dc.identifier.other | http://dissertations.umi.com/ku:13532 | |
dc.identifier.uri | http://hdl.handle.net/1808/22548 | |
dc.description.abstract | Manganese centers that react with O2 and its reduced derivatives mediate a diverse array of biologically important reactions including the detoxification of superoxide, the conversion of nucleotides to deoxynucleotides, and the generation of O2 from H2O. Peroxo-, oxo-, and hydroxo-manganese motifs are frequently invoked in the catalytic cycles of Mn enzymes. To that end, biomimetic complexes featuring peroxo-, oxo-, and hydroxo-manganese adducts were synthesized and studied using spectroscopic techniques, including variable-temperature electronic absorption, electron paramagnetic resonance (EPR), X-ray absorption (XAS), and magnetic circular dichroism (MCD) spectroscopies along with computational methods, such as density functional theory (DFT) and time-dependent DFT. The structural and spectroscopic properties of these species were investigated in order to better understand how the geometric and electronic structure of these complexes affects reactivity. | |
dc.format.extent | 296 pages | |
dc.language.iso | en | |
dc.publisher | University of Kansas | |
dc.rights | Copyright held by the author. | |
dc.subject | Chemistry | |
dc.subject | biomimetic | |
dc.subject | Manganese | |
dc.subject | oxo | |
dc.subject | peroxo | |
dc.subject | reactivity | |
dc.subject | spectroscopy | |
dc.title | Biomimetic Peroxo- and Oxo-manganese Complexes: Insights into Structure and Reactivity through Kinetic, Spectroscopic, and Computational Studies | |
dc.type | Dissertation | |
dc.contributor.cmtemember | Barybin, Mikhail | |
dc.contributor.cmtemember | Bowman-James, Kristin | |
dc.contributor.cmtemember | Ren, Shenqiang | |
dc.contributor.cmtemember | Scurto, Aaron | |
dc.thesis.degreeDiscipline | Chemistry | |
dc.thesis.degreeLevel | Ph.D. | |
dc.rights.accessrights | openAccess | |