Bubble dynamics and size distributions during focused ultrasound insonation
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Issue Date
2004Author
Yang, Xinmai
Roy, Ronald A.
Holt, R. Glynn
Publisher
Acoustical Society of America
Type
Article
Article Version
Scholarly/refereed, publisher version
Metadata
Show full item recordAbstract
The deposition of ultrasonic energy in tissue can cause tissue damage due to local heating. For pressures above a critical threshold, cavitation will occur, inducing a much larger thermal energy deposition in a local region. The present work develops a nonlinear bubble dynamicsmodel to numerically investigate bubble oscillations and bubble-enhanced heating during focused ultrasound (HIFU) insonation. The model is applied to calculate two threshold-dependent phenomena occurring for nonlinearly oscillating bubbles: Shape instability and growth by rectified diffusion. These instabilities in turn are shown to place physical boundaries on the time-dependent bubble size distribution, and thus the thermal energy deposition.
Description
This is the published version. Copyright © 2004 Acoustical Society of America
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Citation
Yang, Xinmai, Ronald A. Roy, and R. Glynn Holt. "Bubble Dynamics and Size Distributions during Focused Ultrasound Insonation." The Journal of the Acoustical Society of America J. Acoust. Soc. Am. 116.6 (2004): 3423. http://dx.doi.org/10.1121/1.1823251
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