Research Centers: Recent submissions
Now showing items 21-40 of 236
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Preliminary Evidence That Fiji Water Has Protective Effects against Aluminum Toxicity in Honey Bees (Apis mellifera)
(MDPI, 2023-02-20)Researchers have determined that bioavailable aluminum chloride (AlCl3) may affect honey bee behavior (e.g., foraging patterns and locomotion) and physiology (e.g., abdominal spasms). The purpose of these experiments was ... -
A Simple Micromilled Microfluidic Impedance Cytometer with Vertical Parallel Electrodes for Cell Viability Analysis
(MDPI, 2023-01-22)Microfluidic impedance cytometry has been demonstrated as an effective platform for single cell analysis, taking advantage of microfabricated features and dielectric cell sensing methods. In this study, we present a simple ... -
Proceedings of the 2023 Hawk Talks
(Biotechnology Program, University of Kansas Edwards Campus, 2023-04-28)The 2023 Hawk Talks Conference features work from students representing a diverse range of programs, including Applied Biological Sciences, American Sign Language and Deaf Studies, Psychology, and Biotechnology. Hawk Talks ... -
Heterogeneous melting near the Thwaites Glacier grounding line
(Nature Research, 2023-02-15)Thwaites Glacier represents 15% of the ice discharge from the West Antarctic Ice Sheet and influences a wider catchment1,2,3. Because it is grounded below sea level4,5, Thwaites Glacier is thought to be susceptible to ... -
Pseudomonas aeruginosa Dps (PA0962) Functions in H2O2 Mediated Oxidative Stress Defense and Exhibits In Vitro DNA Cleaving Activity
(MDPI, 2023-02-28)We report the structural, biochemical, and functional characterization of the product of gene PA0962 from Pseudomonas aeruginosa PAO1. The protein, termed Pa Dps, adopts the Dps subunit fold and oligomerizes into a nearly ... -
Native Microbes Amplify Native Seedling Establishment and Diversity While Inhibiting a Non-Native Grass
(MDPI, 2023-03-06)Although several studies have shown increased native plant establishment with native microbe soil amendments, few studies have investigated how microbes can alter seedling recruitment and establishment in the presence of ... -
Phylogenetic Signal, Root Morphology, Mycorrhizal Type, and Macroinvertebrate Exclusion: Exploring Wood Decomposition in Soils Conditioned by 13 Temperate Tree Species
(MDPI, 2022-03-30)Woodlands are pivotal to carbon stocks, but the process of cycling C is slow and may be most effective in the biodiverse root zone. How the root zone impacts plants has been widely examined over the past few decades, but ... -
Direct and Indirect Competitive Interactions between Ooencyrtus nezarae and Paratelenomus saccharalis Parasitizing Megacopta cribraria Egg Patches
(MDPI, 2022-12-30)The present study investigated egg parasitoid interspecific interactions between a generalist, Ooencyrtus nezarae Ishii (Hymenoptera: Encyrtidae) and a specialist, Paratelenomus saccharalis Dodd (Hymenoptera: Platygastridae) ... -
Role of plant relatedness in plant–soil feedback dynamics of sympatric Asclepias species
(Wiley Open Access, 2023-01-24)Plants affect associated biotic and abiotic edaphic factors, with reciprocal feedbacks from soil characteristics affecting plants. These two-way interactions between plants and soils are collectively known as plant–soil ... -
Predicting the structure of large protein complexes using AlphaFold and Monte Carlo tree search
(Nature Research, 2022-10-12)AlphaFold can predict the structure of single- and multiple-chain proteins with very high accuracy. However, the accuracy decreases with the number of chains, and the available GPU memory limits the size of protein complexes ... -
Novel compound C150 inhibits pancreatic cancer through induction of ER stress and proteosome assembly
(Frontiers Media, 2022-10-05)Pancreatic cancer is a devastating disease with a dismal prognosis and poor treatment outcomes. Searching for new agents for pancreatic cancer treatment is of great significance. We previously identified a novel activity ... -
DNAJA1- and conformational mutant p53-dependent inhibition of cancer cell migration by a novel compound identified through a virtual screen
(Springer Nature, 2022-10-31)Cancers are frequently addicted to oncogenic missense mutant p53 (mutp53). DNAJA1, a member of heat shock protein 40 (HSP40), also known as J-domain proteins (JDPs), plays a crucial role in the stabilization and oncogenic ... -
ADAMTSL2 gene variant in patients with features of autosomal dominant connective tissue disorders
(Wiley, 2020-12-27)Ehlers-Danlos syndrome (EDS) consists of a heterogeneous group of genetically inherited connective tissue disorders. A family with three affected members over two generations with features of Dermatosparaxic EDS (dEDS) ... -
The complete mitogenome of an undescribed clam shrimp of the genus Gondwanalimnadia (Branchiopoda: Spinicaudata), from a temporary wetland in Central District, Botswana
(Taylor and Francis, 2020-02-28)Clam shrimps (Spinicaudata) are a widespread and diverse crustacean group that frequent temporary aquatic habitats, but few complete mitochondrial genomes have been published for this group. Here, we report the mitogenome ... -
The complete mitogenome of the fairy shrimp Streptocephalus cafer (Lovén, 1847) (Crustacea: Branchiopoda: Anostraca) from an ephemeral pond in Botswana, southern Africa
(Taylor and Francis, 2020-01-14)Fairy shrimps (Anostraca) constitute an important component of seasonally aquatic habitats, but few complete mitochondrial genomes have been published for this group. Here, we report the mitogenome of a common southern ... -
Dissecting the Genetic Basis of Variation in Drosophila Sleep Using a Multiparental QTL Mapping Resource
(MDPI, 2020-03-11)There is considerable variation in sleep duration, timing and quality in human populations, and sleep dysregulation has been implicated as a risk factor for a range of health problems. Human sleep traits are known to be ... -
Bacterial but Not Fungal Rhizosphere Community Composition Differ among Perennial Grass Ecotypes under Abiotic Environmental Stress
(American Society for Microbiology, 2022-04-20)Environmental change, especially frequent droughts, is predicted to detrimentally impact the North American perennial grasslands. Consistent dry spells will affect plant communities as well as their associated rhizobiomes, ... -
GWYRE: A Resource for Mapping Variants onto Experimental and Modeled Structures of Human Protein Complexes
(2022-06-15)Rapid progress in structural modeling of proteins and their interactions is powered by advances in knowledge-based methodologies along with better understanding of physical principles of protein structure and function. The ... -
Peptide nanosponges designed for rapid uptake by leukocytes and neural stem cells
(Royal Society of Chemistry, 2018-04-30)The structure of novel binary nanosponges consisting of (cholesterol-(K/D)nDEVDGC)3-trimaleimide units possessing a trigonal maleimide linker, to which either lysine (K)20 or aspartic acid (D)20 are tethered, has been ... -
Discovery of small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase
(Taylor & Francis Open Access, 2022-05-05)Malaria is caused by infection with protozoan parasites of the Plasmodium genus, which is part of the phylum Apicomplexa. Most organisms in this phylum contain a relic plastid called the apicoplast. The apicoplast genome ...