ATTENTION: The software behind KU ScholarWorks is being upgraded to a new version. Starting July 15th, users will not be able to log in to the system, add items, nor make any changes until the new version is in place at the end of July. Searching for articles and opening files will continue to work while the system is being updated.
If you have any questions, please contact Marianne Reed at mreed@ku.edu .
Inhibition of Acinetobacter baumannii, Staphylococcus aureus and Pseudomonas aeruginosa biofilm formation with a class of TAGE-triazole conjugates
dc.contributor.author | Huigens, Robert W., III | |
dc.contributor.author | Rogers, Steven A. | |
dc.contributor.author | Steinhauer, Andrew T. | |
dc.contributor.author | Melander, Christian | |
dc.date.accessioned | 2015-11-20T23:05:36Z | |
dc.date.available | 2015-11-20T23:05:36Z | |
dc.date.issued | 2009-01-12 | |
dc.identifier.citation | Iii, Robert W. Huigens, Steven A. Rogers, Andrew T. Steinhauer, and Christian Melander. "Inhibition of Acinetobacter Baumannii, Staphylococcus Aureus and Pseudomonas Aeruginosa Biofilm Formation with a Class of TAGE-triazole Conjugates." Organic & Biomolecular Chemistry Org. Biomol. Chem. 7.4 (2009): 794. DOI:10.1039/B817926C | en_US |
dc.identifier.uri | http://hdl.handle.net/1808/18972 | |
dc.description | This is the published version. Copyright Royal Society of Chemistry | en_US |
dc.description.abstract | A chemically diverse library of TAGE-triazole conjugates was synthesized utilizing click chemistry on the TAGE scaffold. This library of small molecules was screened for anti-biofilm activity and found to possess the ability of inhibiting biofilm formation against Acinetobacter baumannii, Staphylococcus aureus and Pseudomonas aeruginosa. One such compound in this library demonstrated the most potent inhibitory effect against Staphylococcus aureus biofilm formation that has been displayed by any 2-aminoimidazole derivative. | en_US |
dc.publisher | Royal Society of Chemistry | en_US |
dc.title | Inhibition of Acinetobacter baumannii, Staphylococcus aureus and Pseudomonas aeruginosa biofilm formation with a class of TAGE-triazole conjugates | en_US |
dc.type | Article | |
kusw.kuauthor | Rogers, Steven A. | |
kusw.kudepartment | Chemistry | en_US |
dc.identifier.doi | 10.1039/B817926C | |
kusw.oaversion | Scholarly/refereed, publisher version | |
kusw.oapolicy | This item meets KU Open Access policy criteria. | |
dc.rights.accessrights | openAccess |