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    Synthesis and bacterial biofilm inhibition studies of ethyl N-(2-phenethyl) carbamate derivatives

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    rogers_synthesis_2010.pdf (174.5Kb)
    Issue Date
    2010-07-08
    Author
    Rogers, Steven A.
    Publisher
    Royal Society of Chemistry
    Type
    Article
    Article Version
    Scholarly/refereed, publisher version
    Metadata
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    Abstract
    An 88 member library based upon the marine bacterial metabolite ethyl N-(2-phenethyl) carbamate was evaluated for bacterial biofilm inhibition against a panel of medically relevant strains. These studies culminated in the discovery of a new class of molecules capable of inhibiting the formation of S. aureus biofilms with low micromolar IC50 values.
    Description
    This is the published version. Copyright Royal Society of Chemistry
    URI
    http://hdl.handle.net/1808/18970
    DOI
    https://doi.org/10.1039/C0OB00063A
    Collections
    • Chemistry Scholarly Works [610]
    Citation
    Rogers, Steven A., Daniel C. Whitehead, Trey Mullikin, and Christian Melander. "Synthesis and Bacterial Biofilm Inhibition Studies of Ethyl N-(2-phenethyl) Carbamate Derivatives." Organic & Biomolecular Chemistry Org. Biomol. Chem. 8.17 (2010): 3857. DOI:10.1039/C0OB00063A

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    Contact KU ScholarWorks
    785-864-8983
    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    785-864-8983

    KU Libraries
    1425 Jayhawk Blvd
    Lawrence, KS 66045
    Image Credits
     

     

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